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- W4386592757 abstract "Insulin was discovered 100 years ago and has been well studied from the perspectives of life and biomedical sciences. This paper reports chemical and biothermodynamic properties of biosynthesis of insulin. This paper reports for the first time the molecular and empirical formulas, biosynthesis reactions, and thermodynamic properties of molecules and their biosynthesis for human preproinsulin, proinsulin, insulin chain A, insulin chain B, insulin, signal peptide and intermediate peptide (C-peptide). Based on these, metabolic reactions were formulated for conversion of preproinsulin to insulin and their thermodynamic feasibility was analyzed.Communicated by Ramaswamy H. Sarma." @default.
- W4386592757 created "2023-09-12" @default.
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- W4386592757 date "2023-09-11" @default.
- W4386592757 modified "2023-09-29" @default.
- W4386592757 title "From genotype to phenotype with biothermodynamics: empirical formulas, biosynthesis reactions and thermodynamic properties of preproinsulin, proinsulin and insulin molecules" @default.
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- W4386592757 doi "https://doi.org/10.1080/07391102.2023.2256880" @default.
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