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- W4386593373 abstract "Cervical cancer (CC) is among the leading causes of cancer-associated mortality in women worldwide; yet the molecular regulators involved in its progression are unclear. This study found that miR-182 was overexpressed in CC tissues when compared with adjacent normal tissues. Moreover, it found that miR-182 expression was significantly positively correlated with distant metastasis in patients with CC. Interestingly, in vitro experiments showed that overexpression and inhibition of miR-182 promoted and suppressed the growth of CC cells, respectively. The tumor-promoting effects of miR-182 on CC progression were achieved via the Wnt/β-catenin axis and its downstream genes. Thus, this study revealed the potential of miR-182/β-catenin as an effective new target for CC treatment." @default.
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- W4386593373 date "2023-01-01" @default.
- W4386593373 modified "2023-09-28" @default.
- W4386593373 title "miR-182 promotes cervical cancer progression via activating the Wnt/β-catenin axis." @default.
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