FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386593485> ?p ?o ?g. }

• W4386593485 abstract "Abstract In mammals, activation of primordial follicles to primary follicle is a progressive and highly regulated process. There is evidence in mice that phosphatase and tensin homologue deleted on Chromosome 10 (PTEN) silencing is an important negative regulator of phosphatidylinositol 3‐kinase (PI3K), which initiates activation of dormant follicles. The objective of the study was to evaluate the effect of the addition of PTEN inhibitor (bpV(HOpic)) (10 μM) and/or Kit Ligand (KL) (100 ng/mL) on the in vitro activation and survival of alpaca primordial follicles. Ovarian cortical fragments from 11 adult alpacas were cultured for 24 h in tissue culture medium (α‐MEM + ) supplemented with KL and bpV or the association of both. Subsequently, each sample was processed by classical histology and follicular counting and classification were performed. The results obtained show a reduction ( p < 0.05) of primordial follicles in more than 50% in follicular tissue cultured in vitro in α‐MEM + or supplemented with bpV and/or KL versus the control (not cultured). Further, >25% increase in primary follicles in follicular tissue cultured in vitro in α‐MEM + or supplemented with KL and/or bpV versus control. However, the follicular survival rate showed a decrease of 20% in the cultured tissues, except for the α‐MEM + supplemented with KL and bpV. In conclusion, supplementation of bpV (HOpic) (10 μM) and KL (100 ng/mL) increased the activation in vitro of primordial follicles and survival after in vitro culture of alpaca ovarian tissue." @default.
• W4386593485 created "2023-09-12" @default.
• W4386593485 creator A5038175554 @default.
• W4386593485 creator A5066002796 @default.
• W4386593485 creator A5092843065 @default.
• W4386593485 date "2023-09-11" @default.
• W4386593485 modified "2023-09-29" @default.
• W4386593485 title "PTEN inhibitor and kit ligand increase in vitro activation and survival of primordial follicles in alpaca" @default.
• W4386593485 cites W1048244319 @default.
• W4386593485 cites W1963625504 @default.
• W4386593485 cites W1965695331 @default.
• W4386593485 cites W1967783128 @default.
• W4386593485 cites W1971744990 @default.
• W4386593485 cites W1995380492 @default.
• W4386593485 cites W2009766889 @default.
• W4386593485 cites W2015201172 @default.
• W4386593485 cites W2018853148 @default.
• W4386593485 cites W2029218543 @default.
• W4386593485 cites W2033472906 @default.
• W4386593485 cites W2036246831 @default.
• W4386593485 cites W2042825674 @default.
• W4386593485 cites W2054544978 @default.
• W4386593485 cites W2059281747 @default.
• W4386593485 cites W2059844002 @default.
• W4386593485 cites W2064242911 @default.
• W4386593485 cites W2072377445 @default.
• W4386593485 cites W2080005628 @default.
• W4386593485 cites W2080669943 @default.
• W4386593485 cites W2082670412 @default.
• W4386593485 cites W2105505249 @default.
• W4386593485 cites W2112516479 @default.
• W4386593485 cites W2121410057 @default.
• W4386593485 cites W2124556975 @default.
• W4386593485 cites W2157485244 @default.
• W4386593485 cites W2161227125 @default.
• W4386593485 cites W2164209208 @default.
• W4386593485 cites W2166208596 @default.
• W4386593485 cites W2464470869 @default.
• W4386593485 cites W2808493845 @default.
• W4386593485 cites W2884303503 @default.
• W4386593485 cites W2903956388 @default.
• W4386593485 cites W2921031674 @default.
• W4386593485 cites W2946279465 @default.
• W4386593485 cites W2964541741 @default.
• W4386593485 cites W2981803673 @default.
• W4386593485 cites W2991059162 @default.
• W4386593485 cites W3081681094 @default.
• W4386593485 cites W4210783695 @default.
• W4386593485 doi "https://doi.org/10.1111/ahe.12961" @default.
• W4386593485 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37694739" @default.
• W4386593485 hasPublicationYear "2023" @default.
• W4386593485 type Work @default.
• W4386593485 citedByCount "0" @default.
• W4386593485 crossrefType "journal-article" @default.
• W4386593485 hasAuthorship W4386593485A5038175554 @default.
• W4386593485 hasAuthorship W4386593485A5066002796 @default.
• W4386593485 hasAuthorship W4386593485A5092843065 @default.
• W4386593485 hasConcept C126322002 @default.
• W4386593485 hasConcept C134018914 @default.
• W4386593485 hasConcept C153911025 @default.
• W4386593485 hasConcept C16685009 @default.
• W4386593485 hasConcept C187785154 @default.
• W4386593485 hasConcept C196843134 @default.
• W4386593485 hasConcept C202751555 @default.
• W4386593485 hasConcept C2776188440 @default.
• W4386593485 hasConcept C2776690073 @default.
• W4386593485 hasConcept C2777609662 @default.
• W4386593485 hasConcept C2779549131 @default.
• W4386593485 hasConcept C2780536345 @default.
• W4386593485 hasConcept C54355233 @default.
• W4386593485 hasConcept C5512455 @default.
• W4386593485 hasConcept C62478195 @default.
• W4386593485 hasConcept C71924100 @default.
• W4386593485 hasConcept C86554907 @default.
• W4386593485 hasConcept C86803240 @default.
• W4386593485 hasConcept C87073359 @default.
• W4386593485 hasConcept C95444343 @default.
• W4386593485 hasConceptScore W4386593485C126322002 @default.
• W4386593485 hasConceptScore W4386593485C134018914 @default.
• W4386593485 hasConceptScore W4386593485C153911025 @default.
• W4386593485 hasConceptScore W4386593485C16685009 @default.
• W4386593485 hasConceptScore W4386593485C187785154 @default.
• W4386593485 hasConceptScore W4386593485C196843134 @default.
• W4386593485 hasConceptScore W4386593485C202751555 @default.
• W4386593485 hasConceptScore W4386593485C2776188440 @default.
• W4386593485 hasConceptScore W4386593485C2776690073 @default.
• W4386593485 hasConceptScore W4386593485C2777609662 @default.
• W4386593485 hasConceptScore W4386593485C2779549131 @default.
• W4386593485 hasConceptScore W4386593485C2780536345 @default.
• W4386593485 hasConceptScore W4386593485C54355233 @default.
• W4386593485 hasConceptScore W4386593485C5512455 @default.
• W4386593485 hasConceptScore W4386593485C62478195 @default.
• W4386593485 hasConceptScore W4386593485C71924100 @default.
• W4386593485 hasConceptScore W4386593485C86554907 @default.
• W4386593485 hasConceptScore W4386593485C86803240 @default.
• W4386593485 hasConceptScore W4386593485C87073359 @default.
• W4386593485 hasConceptScore W4386593485C95444343 @default.
• W4386593485 hasFunder F4320335542 @default.
• W4386593485 hasLocation W43865934851 @default.
• W4386593485 hasLocation W43865934852 @default.

• next