FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386594457> ?p ?o ?g. }

• W4386594457 abstract "Hypertension induces vascular damage followed by organ damage, including heart failure in hypertensive heart disease (HHD) and nephrosclerosis (the resultant renal pathologic change from long-standing hypertension affecting renal vascular supply), ultimately causing renal failure. Renin-angiotensin-aldosterone system (RAAS) inhibitors are well known as effective drugs for the treatment of hypertension and the anti-remodeling of affected organs. A 52-year-old male was evaluated. Right atrophic kidney and proteinuria were noted in his high school years; however, he had no symptoms for about 35 years. He had pollakiuria in November and oliguria and leg edema in December 2020. The edema deteriorated rapidly, and general fatigue and orthopnea emerged in January 2021. Anasarca, hypertension (198/151 mmHg), tachycardia (115/minute), and hypoxemia (oxygen saturation {SpO2} of 93%) were observed on admission. A bilateral pleural effusion and pulmonary congestion were found on a chest X-ray (CXR) examination. An echocardiogram showed a 22% left ventricle ejection fraction (LVEF). Blood urea nitrogen (BUN) and serum creatinine concentrations were 70 mg/dL and 6.05 mg/dL, respectively. He was diagnosed with nephrosclerosis and HHD-induced cardiac exhaustion. Hemodialysis was started in April 2021. Even though the dry weight was decreased by draining water, cardiomegaly (cardiothoracic ratio {CTR}: 60%), low LVEF (20%-30%), and hypertension, especially diastolic hypertension (140-150/100-120 mmHg), were sustained. After 2 mg of candesartan was added in November 2021, the cardiomegaly, blood pressure (BP), and LVEF were rapidly ameliorated. The CTR and LVEF recovered to 48.5% and 60%, respectively, in April 2022. Statistical analyses showed that the independent factors for CTR were the mean monthly diastolic BP (standard partial regression coefficient {[Formula: see text]}: 0.9058, p<0.0001) and candesartan ([Formula: see text]: -0.7389, p=0.0011) in vital signs and prescribed drugs, respectively. We experienced a case of a significant effect of candesartan treatment against heart failure with reduced ejection fraction (HFrEF) caused by HHD in a hemodialysis patient with nephrosclerosis. Statistical analyses suggested that the improvement of HFrEF resistant to fluid removal by hemodialysis was presumably due to a decrease in diastolic BP caused by a small dose of candesartan." @default.
• W4386594457 created "2023-09-12" @default.
• W4386594457 creator A5036970055 @default.
• W4386594457 creator A5047880957 @default.
• W4386594457 creator A5056744595 @default.
• W4386594457 creator A5090055906 @default.
• W4386594457 date "2023-09-11" @default.
• W4386594457 modified "2023-10-18" @default.
• W4386594457 title "A Case of Significant Improvement of Heart Failure With Reduced Ejection Fraction With a Small Dose of Candesartan in a Hemodialysis Patient With Hypertensive Heart Disease and Nephrosclerosis" @default.
• W4386594457 cites W1857892323 @default.
• W4386594457 cites W1870802869 @default.
• W4386594457 cites W1973439425 @default.
• W4386594457 cites W1986205027 @default.
• W4386594457 cites W2016176503 @default.
• W4386594457 cites W2021784922 @default.
• W4386594457 cites W2030128013 @default.
• W4386594457 cites W2047367002 @default.
• W4386594457 cites W2083622225 @default.
• W4386594457 cites W2115194768 @default.
• W4386594457 cites W2144915294 @default.
• W4386594457 cites W2395642529 @default.
• W4386594457 cites W2592176942 @default.
• W4386594457 cites W2740145423 @default.
• W4386594457 cites W2965474825 @default.
• W4386594457 cites W2966794993 @default.
• W4386594457 cites W3046124395 @default.
• W4386594457 cites W3184530171 @default.
• W4386594457 cites W4224883705 @default.
• W4386594457 cites W4304163261 @default.
• W4386594457 cites W4378949427 @default.
• W4386594457 cites W2138973253 @default.
• W4386594457 doi "https://doi.org/10.7759/cureus.45062" @default.
• W4386594457 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37842366" @default.
• W4386594457 hasPublicationYear "2023" @default.
• W4386594457 type Work @default.
• W4386594457 citedByCount "0" @default.
• W4386594457 crossrefType "journal-article" @default.
• W4386594457 hasAuthorship W4386594457A5036970055 @default.
• W4386594457 hasAuthorship W4386594457A5047880957 @default.
• W4386594457 hasAuthorship W4386594457A5056744595 @default.
• W4386594457 hasAuthorship W4386594457A5090055906 @default.
• W4386594457 hasBestOaLocation W43865944571 @default.
• W4386594457 hasConcept C126322002 @default.
• W4386594457 hasConcept C159641895 @default.
• W4386594457 hasConcept C164705383 @default.
• W4386594457 hasConcept C2778198053 @default.
• W4386594457 hasConcept C2779744138 @default.
• W4386594457 hasConcept C2780036600 @default.
• W4386594457 hasConcept C2780045698 @default.
• W4386594457 hasConcept C2908929049 @default.
• W4386594457 hasConcept C71924100 @default.
• W4386594457 hasConcept C78085059 @default.
• W4386594457 hasConcept C84393581 @default.
• W4386594457 hasConceptScore W4386594457C126322002 @default.
• W4386594457 hasConceptScore W4386594457C159641895 @default.
• W4386594457 hasConceptScore W4386594457C164705383 @default.
• W4386594457 hasConceptScore W4386594457C2778198053 @default.
• W4386594457 hasConceptScore W4386594457C2779744138 @default.
• W4386594457 hasConceptScore W4386594457C2780036600 @default.
• W4386594457 hasConceptScore W4386594457C2780045698 @default.
• W4386594457 hasConceptScore W4386594457C2908929049 @default.
• W4386594457 hasConceptScore W4386594457C71924100 @default.
• W4386594457 hasConceptScore W4386594457C78085059 @default.
• W4386594457 hasConceptScore W4386594457C84393581 @default.
• W4386594457 hasLocation W43865944571 @default.
• W4386594457 hasLocation W43865944572 @default.
• W4386594457 hasOpenAccess W4386594457 @default.
• W4386594457 hasPrimaryLocation W43865944571 @default.
• W4386594457 hasRelatedWork W1484030157 @default.
• W4386594457 hasRelatedWork W1971710084 @default.
• W4386594457 hasRelatedWork W2028196543 @default.
• W4386594457 hasRelatedWork W2072108749 @default.
• W4386594457 hasRelatedWork W2398108170 @default.
• W4386594457 hasRelatedWork W2481234813 @default.
• W4386594457 hasRelatedWork W2891746874 @default.
• W4386594457 hasRelatedWork W2920829402 @default.
• W4386594457 hasRelatedWork W3164268473 @default.
• W4386594457 hasRelatedWork W4207030337 @default.
• W4386594457 isParatext "false" @default.
• W4386594457 isRetracted "false" @default.
• W4386594457 workType "article" @default.