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• W4386601716 endingPage "1890" @default.
• W4386601716 startingPage "1890" @default.
• W4386601716 abstract "The DnaA protein has long been considered to play the key role in the initiation of chromosome replication in modern bacteria. Many questions about this role, however, remain unanswered. Here, we raise these questions within a framework based on the dynamics of hyperstructures, alias large assemblies of molecules and macromolecules that perform a function. In these dynamics, hyperstructures can (1) emit and receive signals or (2) fuse and separate from one another. We ask whether the DnaA-based initiation hyperstructure acts as a logic gate receiving information from the membrane, the chromosome, and metabolism to trigger replication; we try to phrase some of these questions in terms of DNA supercoiling, strand opening, glycolytic enzymes, SeqA, ribonucleotide reductase, the macromolecular synthesis operon, post-translational modifications, and metabolic pools. Finally, we ask whether, underpinning the regulation of the cell cycle, there is a physico-chemical clock inherited from the first protocells, and whether this clock emits a single signal that triggers both chromosome replication and cell division." @default.
• W4386601716 created "2023-09-12" @default.
• W4386601716 creator A5045319866 @default.
• W4386601716 creator A5057700006 @default.
• W4386601716 creator A5077550115 @default.
• W4386601716 date "2023-09-10" @default.
• W4386601716 modified "2023-10-17" @default.
• W4386601716 title "Open Questions about the Roles of DnaA, Related Proteins, and Hyperstructure Dynamics in the Cell Cycle" @default.
• W4386601716 cites W1502935855 @default.
• W4386601716 cites W1513376553 @default.
• W4386601716 cites W1513442717 @default.
• W4386601716 cites W1530539563 @default.
• W4386601716 cites W1532582484 @default.
• W4386601716 cites W1542151197 @default.
• W4386601716 cites W1545203638 @default.
• W4386601716 cites W1553669032 @default.
• W4386601716 cites W1558073946 @default.
• W4386601716 cites W1558570590 @default.
• W4386601716 cites W1563095561 @default.
• W4386601716 cites W1568254450 @default.
• W4386601716 cites W1578858788 @default.
• W4386601716 cites W1592336336 @default.
• W4386601716 cites W1615461297 @default.
• W4386601716 cites W1628431976 @default.
• W4386601716 cites W1833890159 @default.
• W4386601716 cites W1856728459 @default.
• W4386601716 cites W1884895713 @default.
• W4386601716 cites W1906730395 @default.
• W4386601716 cites W1935017661 @default.
• W4386601716 cites W1939028897 @default.
• W4386601716 cites W1945505508 @default.
• W4386601716 cites W1964208832 @default.
• W4386601716 cites W1964601681 @default.
• W4386601716 cites W1965778416 @default.
• W4386601716 cites W1968101639 @default.
• W4386601716 cites W1969434681 @default.
• W4386601716 cites W1974509082 @default.
• W4386601716 cites W1975820695 @default.
• W4386601716 cites W1975982665 @default.
• W4386601716 cites W1976743212 @default.
• W4386601716 cites W1978662672 @default.
• W4386601716 cites W1979520135 @default.
• W4386601716 cites W1979564285 @default.
• W4386601716 cites W1981242451 @default.
• W4386601716 cites W1987908562 @default.
• W4386601716 cites W1987939643 @default.
• W4386601716 cites W1988523786 @default.
• W4386601716 cites W1990520494 @default.
• W4386601716 cites W1994132314 @default.
• W4386601716 cites W1996336244 @default.
• W4386601716 cites W1998620676 @default.
• W4386601716 cites W2001831501 @default.
• W4386601716 cites W2004801113 @default.
• W4386601716 cites W2005160671 @default.
• W4386601716 cites W2008828383 @default.
• W4386601716 cites W2012269327 @default.
• W4386601716 cites W2015908576 @default.
• W4386601716 cites W2017340257 @default.
• W4386601716 cites W2020573583 @default.
• W4386601716 cites W2022613882 @default.
• W4386601716 cites W2022731203 @default.
• W4386601716 cites W2025517341 @default.
• W4386601716 cites W2025579355 @default.
• W4386601716 cites W2026274581 @default.
• W4386601716 cites W2026535633 @default.
• W4386601716 cites W2026653549 @default.
• W4386601716 cites W2028914339 @default.
• W4386601716 cites W2030907175 @default.
• W4386601716 cites W2032834395 @default.
• W4386601716 cites W2035264447 @default.
• W4386601716 cites W2040945279 @default.
• W4386601716 cites W2042385787 @default.
• W4386601716 cites W2046503168 @default.
• W4386601716 cites W2047174640 @default.
• W4386601716 cites W2047228870 @default.
• W4386601716 cites W2052674054 @default.
• W4386601716 cites W2054118983 @default.
• W4386601716 cites W2055084238 @default.
• W4386601716 cites W2055236285 @default.
• W4386601716 cites W2058470715 @default.
• W4386601716 cites W2060916451 @default.
• W4386601716 cites W2061135731 @default.
• W4386601716 cites W2061228928 @default.
• W4386601716 cites W2063045156 @default.
• W4386601716 cites W2064522981 @default.
• W4386601716 cites W2065007625 @default.
• W4386601716 cites W2067728003 @default.
• W4386601716 cites W2069267306 @default.
• W4386601716 cites W2071612028 @default.
• W4386601716 cites W2076593875 @default.
• W4386601716 cites W2079661679 @default.
• W4386601716 cites W2081122054 @default.
• W4386601716 cites W2082065029 @default.
• W4386601716 cites W2082861064 @default.
• W4386601716 cites W2083874809 @default.
• W4386601716 cites W2084087825 @default.
• W4386601716 cites W2084149265 @default.
• W4386601716 cites W2085768119 @default.

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