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- W4386611541 abstract "Drug discovery comprises all the activities involved in transforming a compound from a drug candidate to a product approved for marketable form and gaining regulatory permission to market it for use in the target indication(s). Bioinformatics, as related to genetics and genomics, is a scientific subdiscipline that involves using software tools to collect, store, compare, analyze and understand biological data and information, such as DNA, RNA, or protein and amino acid sequences or annotations about those sequences. The various innovative approaches in drug discovery include gene sequencing strategies, the role of bioinformatics, tissue expression patterns for target validation, ultra-high-throughput screening for lead identification, biology and chemistry approaches for developability screens, and finally the selection of a candidate molecule for clinical development. The above methodologies are incorporated in this chapter in detail. The overall detail explicates the progression of molecular targets to novel therapeutics under a new paradigm for drug discovery. These details will be useful for researchers working in the domain of drug discovery and pharmacoinformatics and eventually may help bring more effective drugs to patients." @default.
- W4386611541 created "2023-09-12" @default.
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- W4386611541 date "2023-01-01" @default.
- W4386611541 modified "2023-09-29" @default.
- W4386611541 title "Innovative Strategies in Drug Discovery and Pharmacoinformatics" @default.
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- W4386611541 doi "https://doi.org/10.1007/978-981-99-2302-1_7" @default.
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