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- W4386645178 abstract "To evaluate whether the degree of antenatal hydronephrosis and related antenatal ultrasound findings are associated with the need of postnatal surgery. A retrospective cohort of isolated fetal hydronephrosis was investigated. We included fetuses with antero-posterior renal pelvic diameter (APRPD) measured ≥ 10 mm, or ≥ 7 mm with calyceal dilatation, evaluated at our Prenatal Diagnosis Center between 2009 and 2014. Multiple pregnancies or pregnancies complicated by associated fetal structural abnormalities, aneuploidy or stillbirth were excluded. Ultrasound and follow up data were retrieved from the Prenatal Diagnosis Center database and from the records of the pediatric surgery department. Diagnostic performances of APRPD, dilated fetal ureter and dilated calyceal system, recorded at last scan before delivery, were evaluated for prediction of postnatal surgery. P < 0.05 was considered significant. We reported 99 cases of fetal hydronephrosis. Postnatal surgery was required in 35/99 (Group A). Surgery was not required in 51/99 cases (Group B).We excluded from our analysis 7/99 patients because of associated anomalies or renal dysplasia detected postnatally. Six out of 99 cases were lost at follow up. In group A median APRPD was 18 mm (IQR 12 to 25), in group B 11 mm (IQR 10 to 14); this difference was statistically significant (p < 0.0001). Calyceal system dilatation was present in 18/35 fetuses in group A and in 21/51 fetuses in group B (p = 0.3). Fetal ureteral dilatation was recorded in 13/35 fetuses in group A and 11/51 in group B (p = 0.11). Sensitivity and specificity for postnatal surgery were 55% and 83% for APRPD ≥ 15 mm. Likelihood ratio (+) and Likelihood ratio (−) were respectively 3.2 and 0.54. APRPD ≥ 15 mm slightly increases the risk of postnatal surgery in fetuses with isolated hydronephrosis. However antenatal detection of fetal calyceal system or ureteral dilatation was not associated with an increased risk of postnatal surgery." @default.
- W4386645178 created "2023-09-13" @default.
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- W4386645178 date "2016-09-01" @default.
- W4386645178 modified "2023-10-18" @default.
- W4386645178 title "P25.03: Prediction of postnatal surgery in fetuses with isolated hydronephrosis" @default.
- W4386645178 doi "https://doi.org/10.1002/uog.16740" @default.
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