FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386660684> ?p ?o ?g. }

• W4386660684 abstract "Abstract Background Allogeneic and autologous hematopoietic stem cell transplantation (HSCT) are potential curative treatments for several hematological malignancies (1). Survival after HSCT has improved over the last decade, but survivors remain at risk for health issues after transplantation. Cardiovascular complications after HSCT are increasingly recognized (2). Cardiovascular diseases may be an important cause of mortality and morbidity in patients after HSCT owing to the toxicities of the cancer therapies; however, the incidence of cardiovascular events (CVEs) in this population has not been completely characterized. The objective of this systematic review is to summarize the evidence on the incidence of CVEs in HSCT recipients. Methods Medline and Embase were searched from inception to December 2020 without language restriction. Two authors independently screened the titles and abstracts. Inclusion criteria were: cohort studies and phase 3 randomized controlled trials that reported CVEs (i.e., heart failure, arrythmias, acute coronary syndrome, and stroke) or cardiovascular death among adults who underwent HSCT for a hematological malignancy. All-cause mortality, relapse-related mortality, and non-relapse-related mortality (NRM) were also collected. Studies in which the follow up period was not started immediately after HSCT were excluded due to the risk of immortal bias. Results Of 8151 nonduplicate articles, 30 studies including 14019 individuals post autologous HSCT, and 22 studies including 31049 individuals post allogeneic HSCT met the inclusion criteria. The cumulative incidence of CVEs in the first 100 days post autologous HSCT was 9% and arrhythmia (i.e., atrial fibrillation) was the most common CVE. In recipients of allogeneic HSCT, the 100-day cumulative incidence of CVEs was 3%, and heart failure (HF) was the most common reported CVE. In recipients of autologous and allogeneic HSCT, cardiovascular death was responsible for 43% and 10% of NRM within 100 days, respectively (Table 1). The incidence of CVEs was 4.96 per 1000-person years (95% CI; 4.21–5.80) in long-term survivors (beyond 100-days) of autologous HSCT, and HF was the most common CVE in this population. In long-term survivors of allogeneic HSCT, the incidence of CVEs was 1.90 per 1000-person years (95% CI: 1.59–2.24). Cardiovascular death was the most frequently reported CVE in long-term survivors of allogeneic HSCT (Table 2). Conclusion CVEs remain a major cause of non relapse morbidity and mortality in recipients of HSCT, especially recipients of autologous HSCT within the first 100 days. Future studies are needed to identify the risk factors for CVEs that are specific to HSCT recipients. Funding Acknowledgement Type of funding sources: None." @default.
• W4386660684 created "2023-09-13" @default.
• W4386660684 creator A5014346242 @default.
• W4386660684 creator A5023965566 @default.
• W4386660684 creator A5027237754 @default.
• W4386660684 creator A5027492216 @default.
• W4386660684 creator A5042163217 @default.
• W4386660684 creator A5043938492 @default.
• W4386660684 creator A5046987520 @default.
• W4386660684 creator A5053253072 @default.
• W4386660684 creator A5069359085 @default.
• W4386660684 creator A5074444538 @default.
• W4386660684 creator A5080807751 @default.
• W4386660684 date "2021-10-01" @default.
• W4386660684 modified "2023-09-26" @default.
• W4386660684 title "Cardiovascular events among recipients of hematopoietic stem cell transplantation" @default.
• W4386660684 doi "https://doi.org/10.1093/eurheartj/ehab724.2876" @default.
• W4386660684 hasPublicationYear "2021" @default.
• W4386660684 type Work @default.
• W4386660684 citedByCount "0" @default.
• W4386660684 crossrefType "journal-article" @default.
• W4386660684 hasAuthorship W4386660684A5014346242 @default.
• W4386660684 hasAuthorship W4386660684A5023965566 @default.
• W4386660684 hasAuthorship W4386660684A5027237754 @default.
• W4386660684 hasAuthorship W4386660684A5027492216 @default.
• W4386660684 hasAuthorship W4386660684A5042163217 @default.
• W4386660684 hasAuthorship W4386660684A5043938492 @default.
• W4386660684 hasAuthorship W4386660684A5046987520 @default.
• W4386660684 hasAuthorship W4386660684A5053253072 @default.
• W4386660684 hasAuthorship W4386660684A5069359085 @default.
• W4386660684 hasAuthorship W4386660684A5074444538 @default.
• W4386660684 hasAuthorship W4386660684A5080807751 @default.
• W4386660684 hasBestOaLocation W43866606841 @default.
• W4386660684 hasConcept C120665830 @default.
• W4386660684 hasConcept C121332964 @default.
• W4386660684 hasConcept C126322002 @default.
• W4386660684 hasConcept C127413603 @default.
• W4386660684 hasConcept C177713679 @default.
• W4386660684 hasConcept C187212893 @default.
• W4386660684 hasConcept C2777408962 @default.
• W4386660684 hasConcept C2779134260 @default.
• W4386660684 hasConcept C2780645631 @default.
• W4386660684 hasConcept C2908647359 @default.
• W4386660684 hasConcept C2911091166 @default.
• W4386660684 hasConcept C29374701 @default.
• W4386660684 hasConcept C61511704 @default.
• W4386660684 hasConcept C71924100 @default.
• W4386660684 hasConcept C72563966 @default.
• W4386660684 hasConcept C78519656 @default.
• W4386660684 hasConcept C88879693 @default.
• W4386660684 hasConcept C99454951 @default.
• W4386660684 hasConceptScore W4386660684C120665830 @default.
• W4386660684 hasConceptScore W4386660684C121332964 @default.
• W4386660684 hasConceptScore W4386660684C126322002 @default.
• W4386660684 hasConceptScore W4386660684C127413603 @default.
• W4386660684 hasConceptScore W4386660684C177713679 @default.
• W4386660684 hasConceptScore W4386660684C187212893 @default.
• W4386660684 hasConceptScore W4386660684C2777408962 @default.
• W4386660684 hasConceptScore W4386660684C2779134260 @default.
• W4386660684 hasConceptScore W4386660684C2780645631 @default.
• W4386660684 hasConceptScore W4386660684C2908647359 @default.
• W4386660684 hasConceptScore W4386660684C2911091166 @default.
• W4386660684 hasConceptScore W4386660684C29374701 @default.
• W4386660684 hasConceptScore W4386660684C61511704 @default.
• W4386660684 hasConceptScore W4386660684C71924100 @default.
• W4386660684 hasConceptScore W4386660684C72563966 @default.
• W4386660684 hasConceptScore W4386660684C78519656 @default.
• W4386660684 hasConceptScore W4386660684C88879693 @default.
• W4386660684 hasConceptScore W4386660684C99454951 @default.
• W4386660684 hasIssue "Supplement_1" @default.
• W4386660684 hasLocation W43866606841 @default.
• W4386660684 hasOpenAccess W4386660684 @default.
• W4386660684 hasPrimaryLocation W43866606841 @default.
• W4386660684 hasRelatedWork W2004368639 @default.
• W4386660684 hasRelatedWork W2006005029 @default.
• W4386660684 hasRelatedWork W2147263480 @default.
• W4386660684 hasRelatedWork W2161996216 @default.
• W4386660684 hasRelatedWork W2360260519 @default.
• W4386660684 hasRelatedWork W2363080410 @default.
• W4386660684 hasRelatedWork W2614629048 @default.
• W4386660684 hasRelatedWork W4206985829 @default.
• W4386660684 hasRelatedWork W4386054571 @default.
• W4386660684 hasRelatedWork W99283317 @default.
• W4386660684 hasVolume "42" @default.
• W4386660684 isParatext "false" @default.
• W4386660684 isRetracted "false" @default.
• W4386660684 workType "article" @default.