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- W4386660686 abstract "Abstract Background To date, sparse data are available with regard to gender differences in coronary plaque morphology and composition as underlying mechanism of MINOCA. Purpose To assess the differences in coronary plaque morphology in culprit lesion between women and men with MINOCA using intravascular optical coherence tomography. Methods Totally, 7404 consecutives acute myocardial infarction patients who underwent emergency coronary angiography between 2016 and 2019 were screened. MINOCA were identified in 292 patients (mean age: 72.6% male, 54.1% with ST-segment elevation). Optical coherence tomography was performed in 190 patients (men, n=142). Results Women with MINOCA were older (62.5±10.6 vs. 54.0±11.5, P<0.001) and more over 55 years (75.3% vs. 43.6%, P<0.001). Although women with MINOCA more frequently presented with NSTEMI (56.8% vs. 41.7%, P=0.025) and prior coronary artery disease (CAD) (33.3% vs. 6.3%, P<0.001), they were less likely smoker (27.2% vs. 58.8%, P<0.001). There was no significant difference in incidence of plaque rupture, erosion and calcified nodule between men and women. However, women were more likely to have thin-cap fibroatheroma (TCFA) (39.6% vs. 22.5%, P=0.025). Conclusion Women with MINOCA were older, more frequently presented with NSTEMI and less smoking compared to men. Besides, more TCFA were observed in women. Funding Acknowledgement Type of funding sources: None. Clinical and OCT plaque profilesProportion of clinical and OCT profiles" @default.
- W4386660686 created "2023-09-13" @default.
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- W4386660686 date "2021-10-01" @default.
- W4386660686 modified "2023-09-27" @default.
- W4386660686 title "Gender-specific difference of clinical and plaque characteristics in myocardial infarction with non-obstructive artery (MINOCA): insights from optical coherence tomography" @default.
- W4386660686 doi "https://doi.org/10.1093/eurheartj/ehab724.1194" @default.
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