Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386688710> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W4386688710 abstract "Objective: Multiple myeloma (MM) is a malignant hematological disease and anemia is observed in the majority of patients. Hepcidin, Growth differentiation factor-15 (GDF-15), soluble transferrin receptor (sTfR) have been investigated in many forms of anemia, especially in chronic diseases and cancers. However, there are few studies investigating their role in MM. We aimed to determine the relationship between hepcidin, sTfR and GDF-15 levels in MM patients and their clinical features such as anemia parameters, disease stage and overall survival.
 Method: Hepcidin, sTfR and GDF-15 levels, as well as clinical and anemia-related parameters, were analyzed in newly diagnosed MM patients and healthy volunteers.
 Result: Although MM patients had significantly lower Hb and Hct levels compared to the control group, none of the GDF-15, hepcidin and sTfR levels showed a significant difference between the groups. Among MM patients, we found that the anemic subgroup had significantly lower hepcidin levels than the non-anemic subgroup. GDF-15, hepcidin and sTfR levels showed weak or moderate positive correlation with each other, while GDF15 was positively correlated with creatinine and sTfR levels were correlated with many parameters such as LDH, CRP, ferritin, albumin, creatinine, Hb and ISS, all of which weak. None of the levels of GDF-15, hepcidin and sTfR had a significant effect on survival. 
 Conclusion: We suggested that these mediators may play a role in anemia of MM but there is not a clear relashionship as in chronic disease anemia, there may be different mechanisms according to the characteristics of the patient groups." @default.
- W4386688710 created "2023-09-13" @default.
- W4386688710 creator A5029035264 @default.
- W4386688710 creator A5061031275 @default.
- W4386688710 creator A5072997171 @default.
- W4386688710 creator A5088893132 @default.
- W4386688710 date "2023-09-12" @default.
- W4386688710 modified "2023-10-18" @default.
- W4386688710 title "The relationship of hepcidin, soluble transferrin receptor, growth differentiation factor-15 and anemia in multipl myeloma" @default.
- W4386688710 doi "https://doi.org/10.18521/ktd.1321364" @default.
- W4386688710 hasPublicationYear "2023" @default.
- W4386688710 type Work @default.
- W4386688710 citedByCount "0" @default.
- W4386688710 crossrefType "journal-article" @default.
- W4386688710 hasAuthorship W4386688710A5029035264 @default.
- W4386688710 hasAuthorship W4386688710A5061031275 @default.
- W4386688710 hasAuthorship W4386688710A5072997171 @default.
- W4386688710 hasAuthorship W4386688710A5088893132 @default.
- W4386688710 hasBestOaLocation W43866887101 @default.
- W4386688710 hasConcept C126322002 @default.
- W4386688710 hasConcept C134018914 @default.
- W4386688710 hasConcept C136935669 @default.
- W4386688710 hasConcept C203014093 @default.
- W4386688710 hasConcept C22814914 @default.
- W4386688710 hasConcept C2775989426 @default.
- W4386688710 hasConcept C2776364478 @default.
- W4386688710 hasConcept C2776485076 @default.
- W4386688710 hasConcept C2776768029 @default.
- W4386688710 hasConcept C2777417653 @default.
- W4386688710 hasConcept C2778248108 @default.
- W4386688710 hasConcept C2778319317 @default.
- W4386688710 hasConcept C2780306776 @default.
- W4386688710 hasConcept C3019673199 @default.
- W4386688710 hasConcept C71924100 @default.
- W4386688710 hasConcept C90924648 @default.
- W4386688710 hasConceptScore W4386688710C126322002 @default.
- W4386688710 hasConceptScore W4386688710C134018914 @default.
- W4386688710 hasConceptScore W4386688710C136935669 @default.
- W4386688710 hasConceptScore W4386688710C203014093 @default.
- W4386688710 hasConceptScore W4386688710C22814914 @default.
- W4386688710 hasConceptScore W4386688710C2775989426 @default.
- W4386688710 hasConceptScore W4386688710C2776364478 @default.
- W4386688710 hasConceptScore W4386688710C2776485076 @default.
- W4386688710 hasConceptScore W4386688710C2776768029 @default.
- W4386688710 hasConceptScore W4386688710C2777417653 @default.
- W4386688710 hasConceptScore W4386688710C2778248108 @default.
- W4386688710 hasConceptScore W4386688710C2778319317 @default.
- W4386688710 hasConceptScore W4386688710C2780306776 @default.
- W4386688710 hasConceptScore W4386688710C3019673199 @default.
- W4386688710 hasConceptScore W4386688710C71924100 @default.
- W4386688710 hasConceptScore W4386688710C90924648 @default.
- W4386688710 hasLocation W43866887101 @default.
- W4386688710 hasOpenAccess W4386688710 @default.
- W4386688710 hasPrimaryLocation W43866887101 @default.
- W4386688710 hasRelatedWork W1996815498 @default.
- W4386688710 hasRelatedWork W2014632439 @default.
- W4386688710 hasRelatedWork W2077070367 @default.
- W4386688710 hasRelatedWork W2342849232 @default.
- W4386688710 hasRelatedWork W2901568353 @default.
- W4386688710 hasRelatedWork W3026441546 @default.
- W4386688710 hasRelatedWork W3030905893 @default.
- W4386688710 hasRelatedWork W4212974731 @default.
- W4386688710 hasRelatedWork W4283721477 @default.
- W4386688710 hasRelatedWork W4289816196 @default.
- W4386688710 isParatext "false" @default.
- W4386688710 isRetracted "false" @default.
- W4386688710 workType "article" @default.