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- W4386691698 endingPage "330" @default.
- W4386691698 startingPage "293" @default.
- W4386691698 abstract "The circadian clock influences almost every aspect of mammalian behavioral, physiological and metabolic processes. Being a hierarchical network, the circadian clock is driven by the central clock in the brain and is composed of several peripheral tissue-specific clocks. It orchestrates and synchronizes the daily oscillations of biological processes to the environment. Several pathological events are influenced by time and seasonal variations and as such implicate the clock in pathogenesis mechanisms. In context with viral infections, circadian rhythmicity is closely associated with host susceptibility, disease severity, and pharmacokinetics and efficacies of antivirals and vaccines. Leveraging the circadian molecular mechanism insights has increased our understanding of clock infection biology and proposes new avenues for viral diagnostics and therapeutics. In this chapter, we address the molecular interplay between the circadian clock and viral infections and discuss the importance of chronotherapy as a complementary approach to conventional medicines, emphasizing the significance of virus-clock studies." @default.
- W4386691698 created "2023-09-13" @default.
- W4386691698 creator A5046960746 @default.
- W4386691698 creator A5083008310 @default.
- W4386691698 creator A5091532434 @default.
- W4386691698 date "2023-01-01" @default.
- W4386691698 modified "2023-10-01" @default.
- W4386691698 title "The interplay between circadian clock and viral infections: A molecular perspective" @default.
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