Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386695579> ?p ?o ?g. }
- W4386695579 abstract "Abstract RNA sequencing (RNAseq) technology has become increasingly important in precision medicine and clinical diagnostics, and emerged as a powerful tool for identifying protein-coding genes, performing differential gene analysis, and inferring immune cell composition. Human peripheral blood samples are widely used for RNAseq, providing valuable insights into individual biomolecular information. Blood samples can be classified as whole blood (WB), plasma, serum, and remaining sediment samples, including plasma-free blood (PFB) and serum-free blood (SFB) samples that are generally considered less useful byproducts during the processes of plasma and serum separation, respectively. However, the feasibility of using PFB and SFB samples for transcriptome analysis remains unclear. In this study, we aimed to assess the suitability of employing PFB or SFB samples as an alternative RNA source in transcriptomic analysis. We performed a comparative analysis of WB, PFB, and SFB samples for different applications. Our results revealed that PFB samples exhibit greater similarity to WB samples than SFB samples in terms of protein-coding gene expression patterns, detection of differentially expressed genes, and immunological characterizations, suggesting that PFB can serve as a viable alternative to WB for transcriptomic analysis. Our study contributes to the optimization of blood sample utilization and the advancement of precision medicine research." @default.
- W4386695579 created "2023-09-14" @default.
- W4386695579 creator A5014881178 @default.
- W4386695579 creator A5021553377 @default.
- W4386695579 creator A5024786337 @default.
- W4386695579 creator A5024987154 @default.
- W4386695579 creator A5035079067 @default.
- W4386695579 creator A5036067677 @default.
- W4386695579 creator A5038316768 @default.
- W4386695579 creator A5041048335 @default.
- W4386695579 creator A5041312244 @default.
- W4386695579 creator A5043404694 @default.
- W4386695579 creator A5043926807 @default.
- W4386695579 creator A5045751980 @default.
- W4386695579 creator A5053177358 @default.
- W4386695579 creator A5062430404 @default.
- W4386695579 creator A5082620355 @default.
- W4386695579 creator A5087204629 @default.
- W4386695579 date "2023-09-13" @default.
- W4386695579 modified "2023-10-18" @default.
- W4386695579 title "Plasma-Free Blood as a Potential Alternative to Whole Blood for Transcriptomic Analysis" @default.
- W4386695579 cites W1581267528 @default.
- W4386695579 cites W1981509058 @default.
- W4386695579 cites W1985987855 @default.
- W4386695579 cites W1995595874 @default.
- W4386695579 cites W2033710859 @default.
- W4386695579 cites W2053003735 @default.
- W4386695579 cites W2073380432 @default.
- W4386695579 cites W2085474000 @default.
- W4386695579 cites W2087366831 @default.
- W4386695579 cites W2104005232 @default.
- W4386695579 cites W2108234281 @default.
- W4386695579 cites W2111281047 @default.
- W4386695579 cites W2114632020 @default.
- W4386695579 cites W2116016263 @default.
- W4386695579 cites W2146512944 @default.
- W4386695579 cites W2165482500 @default.
- W4386695579 cites W2166713489 @default.
- W4386695579 cites W2174471079 @default.
- W4386695579 cites W2510875395 @default.
- W4386695579 cites W2755142955 @default.
- W4386695579 cites W2763864960 @default.
- W4386695579 cites W2770091635 @default.
- W4386695579 cites W2790644446 @default.
- W4386695579 cites W2793159357 @default.
- W4386695579 cites W2809339996 @default.
- W4386695579 cites W2888547849 @default.
- W4386695579 cites W2914524806 @default.
- W4386695579 cites W2939381881 @default.
- W4386695579 cites W2948477377 @default.
- W4386695579 cites W2951912016 @default.
- W4386695579 cites W2963367647 @default.
- W4386695579 cites W2964849163 @default.
- W4386695579 cites W2968722259 @default.
- W4386695579 cites W2980114306 @default.
- W4386695579 cites W2982103369 @default.
- W4386695579 cites W2991341750 @default.
- W4386695579 cites W2994074838 @default.
- W4386695579 cites W2996045117 @default.
- W4386695579 cites W3015451993 @default.
- W4386695579 cites W3035182985 @default.
- W4386695579 cites W3117072641 @default.
- W4386695579 cites W3154433148 @default.
- W4386695579 cites W3159318772 @default.
- W4386695579 cites W3164269777 @default.
- W4386695579 cites W3164271582 @default.
- W4386695579 cites W3170771910 @default.
- W4386695579 cites W3173362574 @default.
- W4386695579 cites W3175752499 @default.
- W4386695579 cites W3177973742 @default.
- W4386695579 cites W3185587603 @default.
- W4386695579 cites W3196610164 @default.
- W4386695579 cites W3206010712 @default.
- W4386695579 cites W3212211726 @default.
- W4386695579 cites W3215774169 @default.
- W4386695579 cites W4221132207 @default.
- W4386695579 cites W4224053983 @default.
- W4386695579 cites W4232909036 @default.
- W4386695579 cites W4281296362 @default.
- W4386695579 cites W4284960597 @default.
- W4386695579 cites W4296932217 @default.
- W4386695579 cites W4309150734 @default.
- W4386695579 cites W4317936732 @default.
- W4386695579 cites W4361269840 @default.
- W4386695579 cites W4386499223 @default.
- W4386695579 doi "https://doi.org/10.1007/s43657-023-00121-1" @default.
- W4386695579 hasPublicationYear "2023" @default.
- W4386695579 type Work @default.
- W4386695579 citedByCount "0" @default.
- W4386695579 crossrefType "journal-article" @default.
- W4386695579 hasAuthorship W4386695579A5014881178 @default.
- W4386695579 hasAuthorship W4386695579A5021553377 @default.
- W4386695579 hasAuthorship W4386695579A5024786337 @default.
- W4386695579 hasAuthorship W4386695579A5024987154 @default.
- W4386695579 hasAuthorship W4386695579A5035079067 @default.
- W4386695579 hasAuthorship W4386695579A5036067677 @default.
- W4386695579 hasAuthorship W4386695579A5038316768 @default.
- W4386695579 hasAuthorship W4386695579A5041048335 @default.
- W4386695579 hasAuthorship W4386695579A5041312244 @default.
- W4386695579 hasAuthorship W4386695579A5043404694 @default.