Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386697054> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W4386697054 abstract "Background and Aims Participation in a healthy lifestyle intervention such as the Diabetes Prevention Program Group Lifestyle Balance–adapted for stroke (GLB-CVA) may reduce stroke burden. Identifying biomarkers associated with lifestyle changes may enhance an individualized approach to stroke recovery. We investigated metabolic biomarkers related to cardiovascular and neurological function in individuals with stroke in the GLB-CVA study and healthy (non-stroke) individuals. Methods and Results Participants with chronic (>12 months) stroke were recruited to this wait-list randomized controlled trial if they were overweight (BMI ≥25 kg/m2). Participants were randomized to (1) the GLB-CVA program to complete 22 educational sessions addressing behavioral principals of dietary and physical activity or (2) a 6 month wait-list control (WLC). Biomarkers [Plasma irisin, vascular endothelial growth factor, lipoprotein-associated phospholipase A2 (Lp-PLA2), insulin-like growth factor 1 and brain-derived neurotrophic factor (BDNF)] were collected at baseline, 3, and 6 months. Age-matched healthy individuals were recruited for biomarker assessment. Compared to healthy adults (n=19), participants with stroke (GLB-CVA=24; WLC=24) at baseline had higher tHcy levels (p<0.001) and lower PLA2 levels (p=0.016). No statistically significant interactions were observed for any biomarkers between the GLB-CVA and WLC or between people who achieved 5% weight loss and those who did not. Conclusion Participation in a 6-month healthy lifestyle program did not result in statistically significant changes to select metabolic biomarker levels for our participants with chronic stroke. However, participants with stroke demonstrated a unique biomarker profile compared to age-matched healthy individuals." @default.
- W4386697054 created "2023-09-14" @default.
- W4386697054 creator A5012039333 @default.
- W4386697054 creator A5017306415 @default.
- W4386697054 creator A5017624227 @default.
- W4386697054 creator A5037268042 @default.
- W4386697054 creator A5048484701 @default.
- W4386697054 creator A5059055200 @default.
- W4386697054 creator A5066925236 @default.
- W4386697054 creator A5077588601 @default.
- W4386697054 date "2023-09-01" @default.
- W4386697054 modified "2023-09-27" @default.
- W4386697054 title "Linking biomarkers with healthy lifestyle outcomes after stroke: Supplementary Results of a 12-month Randomized Controlled Trial" @default.
- W4386697054 doi "https://doi.org/10.1016/j.numecd.2023.09.007" @default.
- W4386697054 hasPublicationYear "2023" @default.
- W4386697054 type Work @default.
- W4386697054 citedByCount "0" @default.
- W4386697054 crossrefType "journal-article" @default.
- W4386697054 hasAuthorship W4386697054A5012039333 @default.
- W4386697054 hasAuthorship W4386697054A5017306415 @default.
- W4386697054 hasAuthorship W4386697054A5017624227 @default.
- W4386697054 hasAuthorship W4386697054A5037268042 @default.
- W4386697054 hasAuthorship W4386697054A5048484701 @default.
- W4386697054 hasAuthorship W4386697054A5059055200 @default.
- W4386697054 hasAuthorship W4386697054A5066925236 @default.
- W4386697054 hasAuthorship W4386697054A5077588601 @default.
- W4386697054 hasConcept C126322002 @default.
- W4386697054 hasConcept C127413603 @default.
- W4386697054 hasConcept C134018914 @default.
- W4386697054 hasConcept C168563851 @default.
- W4386697054 hasConcept C185592680 @default.
- W4386697054 hasConcept C1862650 @default.
- W4386697054 hasConcept C2780586474 @default.
- W4386697054 hasConcept C2780645631 @default.
- W4386697054 hasConcept C2781197716 @default.
- W4386697054 hasConcept C511355011 @default.
- W4386697054 hasConcept C55493867 @default.
- W4386697054 hasConcept C555293320 @default.
- W4386697054 hasConcept C71924100 @default.
- W4386697054 hasConcept C78519656 @default.
- W4386697054 hasConceptScore W4386697054C126322002 @default.
- W4386697054 hasConceptScore W4386697054C127413603 @default.
- W4386697054 hasConceptScore W4386697054C134018914 @default.
- W4386697054 hasConceptScore W4386697054C168563851 @default.
- W4386697054 hasConceptScore W4386697054C185592680 @default.
- W4386697054 hasConceptScore W4386697054C1862650 @default.
- W4386697054 hasConceptScore W4386697054C2780586474 @default.
- W4386697054 hasConceptScore W4386697054C2780645631 @default.
- W4386697054 hasConceptScore W4386697054C2781197716 @default.
- W4386697054 hasConceptScore W4386697054C511355011 @default.
- W4386697054 hasConceptScore W4386697054C55493867 @default.
- W4386697054 hasConceptScore W4386697054C555293320 @default.
- W4386697054 hasConceptScore W4386697054C71924100 @default.
- W4386697054 hasConceptScore W4386697054C78519656 @default.
- W4386697054 hasFunder F4320309663 @default.
- W4386697054 hasFunder F4320337604 @default.
- W4386697054 hasLocation W43866970541 @default.
- W4386697054 hasOpenAccess W4386697054 @default.
- W4386697054 hasPrimaryLocation W43866970541 @default.
- W4386697054 hasRelatedWork W1563850031 @default.
- W4386697054 hasRelatedWork W2045367862 @default.
- W4386697054 hasRelatedWork W2090121162 @default.
- W4386697054 hasRelatedWork W2415759662 @default.
- W4386697054 hasRelatedWork W3036934084 @default.
- W4386697054 hasRelatedWork W3159250744 @default.
- W4386697054 hasRelatedWork W4256514411 @default.
- W4386697054 hasRelatedWork W4292236216 @default.
- W4386697054 hasRelatedWork W4293125060 @default.
- W4386697054 hasRelatedWork W2083697902 @default.
- W4386697054 isParatext "false" @default.
- W4386697054 isRetracted "false" @default.
- W4386697054 workType "article" @default.