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- W4386701314 abstract "Biogenic amines are relevant to human health, however, at high concentrations, some can cause adverse effects. Tyramine and histamine are the ones most associated with food intoxication. The symptoms of tyramine intoxication are increased blood pressure and induce migraine and can cause hypertensive crisis in individuals under MAOI treatment. High levels of tyramine can be found in aged cheese, sausages, and alcoholic beverages. Histamine intoxication is characterized by pruritus, rash, urticaria, and the most incriminated foods are fish and cheese containing excessive amounts of histamine. Nowadays, histamine intolerance, with a wide range of non-specific gastrointestinal, neurological, cardiovascular, respiratory, and skin symptoms, are prevalent with even low histamine levels food. The severity of symptoms is enhanced when metabolization mechanisms are deficient, metabolizing enzymes are inhibited (e.g., drugs), or in the concomitant presence of other bioactive amines, which can enhance and synergistically potentiate toxicity. In addition, some bioactive amines show cytotoxicity at the concentrations usually found in food. indicate the need to expand the studies about their chronic effects. Up to date information is provided in this manuscript allowing a better understanding of the factors involving and affecting intoxications, thereby contributing to their avoidance." @default.
- W4386701314 created "2023-09-14" @default.
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- W4386701314 date "2023-12-01" @default.
- W4386701314 modified "2023-10-16" @default.
- W4386701314 title "Health concerns associated with biogenic amines in food and interaction with amine oxidase drugs" @default.
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- W4386701314 doi "https://doi.org/10.1016/j.cofs.2023.101090" @default.
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