FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386723890> ?p ?o ?g. }

• W4386723890 endingPage "816" @default.
• W4386723890 startingPage "805" @default.
• W4386723890 abstract "BACKGROUND A protective intra-operative lung ventilation strategy has been widely recommended for laparoscopic surgery. However, there is no consensus regarding the optimal level of positive end-expiratory pressure (PEEP) and its effects during pneumoperitoneum. Electrical impedance tomography (EIT) has recently been introduced as a bedside tool to monitor lung ventilation in real-time. OBJECTIVE We hypothesised that individually titrated EIT-PEEP adjusted to the surgical intervention would improve respiratory mechanics during and after surgery. DESIGN Randomised controlled trial. SETTING First Medical Centre of Chinese PLA General Hospital, Beijing. PATIENTS Seventy-five patients undergoing robotic-assisted laparoscopic hepatobiliary and pancreatic surgery under general anaesthesia. INTERVENTIONS Patients were randomly assigned 2 : 1 to individualised EIT-titrated PEEP (PEEP EIT ; n = 50) or traditional PEEP 5 cmH 2 O (PEEP 5 cmH2O ; n = 25). The PEEP EIT group received individually titrated EIT-PEEP during pneumoperitoneum. The PEEP 5 cmH2O group received PEEP of 5 cmH 2 O during pneumoperitoneum. MAIN OUTCOME MEASURES The primary outcome was respiratory system compliance during laparoscopic surgery. Secondary outcomes were individualised PEEP levels, oxygenation, respiratory and haemodynamic status, and occurrence of postoperative pulmonary complications (PPCs) within 7 days. RESULTS Compared with PEEP 5 cmH2O , patients who received PEEP EIT had higher respiratory system compliance (mean values during surgery of 44.3 ± 11.3 vs. 31.9 ± 6.6, ml cmH 2 O −1 ; P < 0.001), lower driving pressure (11.5 ± 2.1 vs. 14.0 ± 2.4 cmH 2 O; P < 0.001), better oxygenation (mean P a O 2 /FiO 2 427.5 ± 28.6 vs. 366.8 ± 36.4; P = 0.003), and less postoperative atelectasis (19.4 ± 1.6 vs. 46.3 ± 14.8 g of lung tissue mass; P = 0.003). Haemodynamic values did not differ significantly between the groups. No adverse effects were observed during surgery. CONCLUSION Individualised PEEP by EIT may improve intra-operative pulmonary mechanics and oxygenation without impairing haemodynamic stability, and decrease postoperative atelectasis. TRIAL REGISTRATION Chinese Clinical Trial Registry (www.chictr.org.cn) identifier: ChiCTR2100045166." @default.
• W4386723890 created "2023-09-14" @default.
• W4386723890 creator A5007980616 @default.
• W4386723890 creator A5015676515 @default.
• W4386723890 creator A5043560507 @default.
• W4386723890 creator A5047299931 @default.
• W4386723890 creator A5051607146 @default.
• W4386723890 creator A5061558038 @default.
• W4386723890 creator A5063188299 @default.
• W4386723890 creator A5066470242 @default.
• W4386723890 creator A5079746187 @default.
• W4386723890 creator A5081534315 @default.
• W4386723890 date "2023-09-13" @default.
• W4386723890 modified "2023-10-06" @default.
• W4386723890 title "Individualised positive end-expiratory pressure titrated intra-operatively by electrical impedance tomography optimises pulmonary mechanics and reduces postoperative atelectasis" @default.
• W4386723890 cites W1622377431 @default.
• W4386723890 cites W1950998820 @default.
• W4386723890 cites W1980449658 @default.
• W4386723890 cites W2028979003 @default.
• W4386723890 cites W2067548806 @default.
• W4386723890 cites W2083892295 @default.
• W4386723890 cites W2139742008 @default.
• W4386723890 cites W2151898076 @default.
• W4386723890 cites W2167431840 @default.
• W4386723890 cites W2282782058 @default.
• W4386723890 cites W2291900475 @default.
• W4386723890 cites W2524943732 @default.
• W4386723890 cites W2551730798 @default.
• W4386723890 cites W2598677501 @default.
• W4386723890 cites W2765432582 @default.
• W4386723890 cites W2791573773 @default.
• W4386723890 cites W2921016641 @default.
• W4386723890 cites W2947556249 @default.
• W4386723890 cites W2948946434 @default.
• W4386723890 cites W2965413706 @default.
• W4386723890 cites W2969063824 @default.
• W4386723890 cites W2989797479 @default.
• W4386723890 cites W3021565337 @default.
• W4386723890 cites W3082035963 @default.
• W4386723890 cites W3140487497 @default.
• W4386723890 cites W81990000 @default.
• W4386723890 doi "https://doi.org/10.1097/eja.0000000000001901" @default.
• W4386723890 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37789753" @default.
• W4386723890 hasPublicationYear "2023" @default.
• W4386723890 type Work @default.
• W4386723890 citedByCount "0" @default.
• W4386723890 crossrefType "journal-article" @default.
• W4386723890 hasAuthorship W4386723890A5007980616 @default.
• W4386723890 hasAuthorship W4386723890A5015676515 @default.
• W4386723890 hasAuthorship W4386723890A5043560507 @default.
• W4386723890 hasAuthorship W4386723890A5047299931 @default.
• W4386723890 hasAuthorship W4386723890A5051607146 @default.
• W4386723890 hasAuthorship W4386723890A5061558038 @default.
• W4386723890 hasAuthorship W4386723890A5063188299 @default.
• W4386723890 hasAuthorship W4386723890A5066470242 @default.
• W4386723890 hasAuthorship W4386723890A5079746187 @default.
• W4386723890 hasAuthorship W4386723890A5081534315 @default.
• W4386723890 hasConcept C126322002 @default.
• W4386723890 hasConcept C126838900 @default.
• W4386723890 hasConcept C127413603 @default.
• W4386723890 hasConcept C136936797 @default.
• W4386723890 hasConcept C141071460 @default.
• W4386723890 hasConcept C155175808 @default.
• W4386723890 hasConcept C163498912 @default.
• W4386723890 hasConcept C163716698 @default.
• W4386723890 hasConcept C200457457 @default.
• W4386723890 hasConcept C2777080012 @default.
• W4386723890 hasConcept C2777714996 @default.
• W4386723890 hasConcept C2778746874 @default.
• W4386723890 hasConcept C2778917391 @default.
• W4386723890 hasConcept C2780047204 @default.
• W4386723890 hasConcept C2781101014 @default.
• W4386723890 hasConcept C42219234 @default.
• W4386723890 hasConcept C70289976 @default.
• W4386723890 hasConcept C71924100 @default.
• W4386723890 hasConcept C78519656 @default.
• W4386723890 hasConceptScore W4386723890C126322002 @default.
• W4386723890 hasConceptScore W4386723890C126838900 @default.
• W4386723890 hasConceptScore W4386723890C127413603 @default.
• W4386723890 hasConceptScore W4386723890C136936797 @default.
• W4386723890 hasConceptScore W4386723890C141071460 @default.
• W4386723890 hasConceptScore W4386723890C155175808 @default.
• W4386723890 hasConceptScore W4386723890C163498912 @default.
• W4386723890 hasConceptScore W4386723890C163716698 @default.
• W4386723890 hasConceptScore W4386723890C200457457 @default.
• W4386723890 hasConceptScore W4386723890C2777080012 @default.
• W4386723890 hasConceptScore W4386723890C2777714996 @default.
• W4386723890 hasConceptScore W4386723890C2778746874 @default.
• W4386723890 hasConceptScore W4386723890C2778917391 @default.
• W4386723890 hasConceptScore W4386723890C2780047204 @default.
• W4386723890 hasConceptScore W4386723890C2781101014 @default.
• W4386723890 hasConceptScore W4386723890C42219234 @default.
• W4386723890 hasConceptScore W4386723890C70289976 @default.
• W4386723890 hasConceptScore W4386723890C71924100 @default.
• W4386723890 hasConceptScore W4386723890C78519656 @default.
• W4386723890 hasIssue "11" @default.
• W4386723890 hasLocation W43867238901 @default.
• W4386723890 hasLocation W43867238902 @default.

• next