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• W4386726500 abstract "It is challenging to recapitulate the natural extracellular matrix’s hierarchical nano/microfibrous three-dimensional (3D) structure with multilevel pores, good mechanical and hydrophilic properties, and excellent bioactivity for designing and developing advanced biomimetic materials. This work reports a new facile strategy for the scalable manufacturing of such a 3D architecture. Natural polymers in an aqueous solution are interpenetrated into a 3D microfibrous matrix with arbitrary shapes and property characteristics to self-assemble in situ into a nanofibrous network. The collagen fiber-like hierarchical structure and interconnected multilevel pores are achieved by self-assembly of the formed nanofibers within the 3D matrix, triggered by a simple cross-linking treatment. The as-prepared alginate/polypropylene biomimetic matrices are bioactive and have a tunable mechanical property (compressive modulus from ∼17 to ∼24 kPa) and a tunable hydrophilicity (water contact angle from ∼94° to 63°). This facile and versatile strategy allows eco-friendly and scalable manufacturing of diverse biomimetic matrices or modification of any existing porous matrices using different polymers." @default.
• W4386726500 created "2023-09-15" @default.
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• W4386726500 date "2023-09-14" @default.
• W4386726500 modified "2023-09-29" @default.
• W4386726500 title "Facile <i>In Situ</i> Assembly of Nanofibers within Three-Dimensional Porous Matrices with Arbitrary Characteristics for Creating Biomimetic Architectures" @default.
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• W4386726500 doi "https://doi.org/10.1021/acs.nanolett.3c02440" @default.
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• W4386726500 hasPublicationYear "2023" @default.
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