Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386755586> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W4386755586 abstract "Our knowledge of the organisation of the human brain at the population-level is yet to translate into power to predict functional differences at the individual-level, limiting clinical applications, and casting doubt on the generalisability of inferred mechanisms. It remains unknown whether the difficulty arises from the absence of individuating biological patterns within the brain, or from limited power to access them with the models and compute at our disposal. Here we comprehensively investigate the resolvability of such patterns with data and compute at unprecedented scale. Across 23810 unique participants from UK Biobank, we systematically evaluate the predictability of 25 individual biological characteristics, from all available combinations of structural and functional neuroimaging data. Over 4526 GPU*hours of computation, we train, optimize, and evaluate out-of-sample 700 individual predictive models, including multilayer perceptrons of demographic, psychological, serological, chronic morbidity, and functional connectivity characteristics, and both uni- and multi-modal 3D convolutional neural network models of macro- and micro-structural brain imaging. We find a marked discrepancy between the high predictability of sex (balanced accuracy 99.7%), age (mean absolute error 2.048 years, R2 0.859), and weight (mean absolute error 2.609Kg, R2 0.625), for which we set new state-of-the-art performance, and the surprisingly low predictability of other characteristics. Neither structural nor functional imaging predicted individual psychology better than the coincidence of common chronic morbidity (p<0.05). Serology predicted common morbidity (p<0.05) and was best predicted by it (p<0.001), followed by structural neuroimaging (p<0.05). Our findings suggest either more informative imaging or more powerful models will be needed to decipher individual level characteristics from the brain." @default.
- W4386755586 created "2023-09-15" @default.
- W4386755586 creator A5007559948 @default.
- W4386755586 creator A5020597757 @default.
- W4386755586 creator A5023050945 @default.
- W4386755586 creator A5058747191 @default.
- W4386755586 creator A5060921300 @default.
- W4386755586 creator A5074881456 @default.
- W4386755586 creator A5076295200 @default.
- W4386755586 creator A5078129443 @default.
- W4386755586 date "2023-08-23" @default.
- W4386755586 modified "2023-10-14" @default.
- W4386755586 title "The legibility of the imaged human brain" @default.
- W4386755586 doi "https://doi.org/10.48550/arxiv.2309.07096" @default.
- W4386755586 hasPublicationYear "2023" @default.
- W4386755586 type Work @default.
- W4386755586 citedByCount "0" @default.
- W4386755586 crossrefType "posted-content" @default.
- W4386755586 hasAuthorship W4386755586A5007559948 @default.
- W4386755586 hasAuthorship W4386755586A5020597757 @default.
- W4386755586 hasAuthorship W4386755586A5023050945 @default.
- W4386755586 hasAuthorship W4386755586A5058747191 @default.
- W4386755586 hasAuthorship W4386755586A5060921300 @default.
- W4386755586 hasAuthorship W4386755586A5074881456 @default.
- W4386755586 hasAuthorship W4386755586A5076295200 @default.
- W4386755586 hasAuthorship W4386755586A5078129443 @default.
- W4386755586 hasBestOaLocation W43867555861 @default.
- W4386755586 hasConcept C105795698 @default.
- W4386755586 hasConcept C111472728 @default.
- W4386755586 hasConcept C116567970 @default.
- W4386755586 hasConcept C138885662 @default.
- W4386755586 hasConcept C149782125 @default.
- W4386755586 hasConcept C154945302 @default.
- W4386755586 hasConcept C15744967 @default.
- W4386755586 hasConcept C169760540 @default.
- W4386755586 hasConcept C180747234 @default.
- W4386755586 hasConcept C197640229 @default.
- W4386755586 hasConcept C23131810 @default.
- W4386755586 hasConcept C2778136018 @default.
- W4386755586 hasConcept C2908647359 @default.
- W4386755586 hasConcept C33923547 @default.
- W4386755586 hasConcept C41008148 @default.
- W4386755586 hasConcept C52338299 @default.
- W4386755586 hasConcept C58693492 @default.
- W4386755586 hasConcept C60644358 @default.
- W4386755586 hasConcept C71924100 @default.
- W4386755586 hasConcept C77350462 @default.
- W4386755586 hasConcept C81363708 @default.
- W4386755586 hasConcept C86803240 @default.
- W4386755586 hasConcept C99454951 @default.
- W4386755586 hasConceptScore W4386755586C105795698 @default.
- W4386755586 hasConceptScore W4386755586C111472728 @default.
- W4386755586 hasConceptScore W4386755586C116567970 @default.
- W4386755586 hasConceptScore W4386755586C138885662 @default.
- W4386755586 hasConceptScore W4386755586C149782125 @default.
- W4386755586 hasConceptScore W4386755586C154945302 @default.
- W4386755586 hasConceptScore W4386755586C15744967 @default.
- W4386755586 hasConceptScore W4386755586C169760540 @default.
- W4386755586 hasConceptScore W4386755586C180747234 @default.
- W4386755586 hasConceptScore W4386755586C197640229 @default.
- W4386755586 hasConceptScore W4386755586C23131810 @default.
- W4386755586 hasConceptScore W4386755586C2778136018 @default.
- W4386755586 hasConceptScore W4386755586C2908647359 @default.
- W4386755586 hasConceptScore W4386755586C33923547 @default.
- W4386755586 hasConceptScore W4386755586C41008148 @default.
- W4386755586 hasConceptScore W4386755586C52338299 @default.
- W4386755586 hasConceptScore W4386755586C58693492 @default.
- W4386755586 hasConceptScore W4386755586C60644358 @default.
- W4386755586 hasConceptScore W4386755586C71924100 @default.
- W4386755586 hasConceptScore W4386755586C77350462 @default.
- W4386755586 hasConceptScore W4386755586C81363708 @default.
- W4386755586 hasConceptScore W4386755586C86803240 @default.
- W4386755586 hasConceptScore W4386755586C99454951 @default.
- W4386755586 hasLocation W43867555861 @default.
- W4386755586 hasOpenAccess W4386755586 @default.
- W4386755586 hasPrimaryLocation W43867555861 @default.
- W4386755586 hasRelatedWork W1530080020 @default.
- W4386755586 hasRelatedWork W1567992464 @default.
- W4386755586 hasRelatedWork W2074764495 @default.
- W4386755586 hasRelatedWork W2540781307 @default.
- W4386755586 hasRelatedWork W2755242398 @default.
- W4386755586 hasRelatedWork W2949871449 @default.
- W4386755586 hasRelatedWork W3124164994 @default.
- W4386755586 hasRelatedWork W3125898096 @default.
- W4386755586 hasRelatedWork W3163027560 @default.
- W4386755586 hasRelatedWork W4366817548 @default.
- W4386755586 isParatext "false" @default.
- W4386755586 isRetracted "false" @default.
- W4386755586 workType "article" @default.