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- W4386762616 abstract "Endosulfan (En) is an organochlorine biocide (OCB), that ends up in the environment due to the enzymatic and microsomal activity even though it is not accumulated in living tissue. Endosulfan acts as an organic micro-pollutant which disrupts land as well as aquatic ecosystem. In the present study, we chemically modified endosulfan and conjugated it with a carrier protein to produce an immune response. The generated antibodies were tested for specificity against En, and characterized before further use. Transition Metal Chalcogenides (TMC) showed excellent optoelectrical potential due to its direct bandgap and distinct physical as well as chemical characteristics. Herein, we synthesized a novel nanohybrid using MoSe2 in combination with graphene oxide (GO) and characterized thoroughly. This was similar to graphene-based metal chalcogenides which were further used in this study to fabricate biosensor for the sensitive detection of En. The in-house developed antibodies (En-Ab) were coupled with the nanohybrid to make MoSe2/GO/En-Ab electrode. Fabricated electrode was tested for electrochemical parameters using differential pulse voltammetry (DPV). Working efficiency of the fabricated electrode i.e., limit of detection (LOD), was found to be 7.45 ppt. In conclusion, we hypothesized that the synthesized TMC nanohybrids could be employed for biosensing of endosulfan, and can likely be developed to test field samples." @default.
- W4386762616 created "2023-09-16" @default.
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- W4386762616 date "2023-12-01" @default.
- W4386762616 modified "2023-09-27" @default.
- W4386762616 title "Two-dimensional layered MoSe2/graphene oxide (GO) nanohybrid coupled with the specific immune-recognition element for rapid detection of endosulfan" @default.
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- W4386762616 doi "https://doi.org/10.1016/j.envres.2023.117127" @default.
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