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- W4386765443 abstract "Abstract Objectives The aim of this study was to evaluate the feasibility of detecting the presence and severity of microleakage of pit and fissure sealant using Quantitative Light-induced Fluorescence (QLF) technology. Methods The areas of interest (AOI) were a total of 160 pit and fissure sites obtained from the occlusal surfaces of 40 permanent teeth. Fluorescent images were acquired using a QLF device, and the ΔF max of each AOI was analysed. After staining and cross-sectioning of the teeth, histological dye penetration was scored on a 0–3 scale. The relationship between ΔF max and microleakage depth was analysed, and the areas under the curve (AUC) were calculated. Results ΔF max showed a significant increase as microleakage depth increased, and a strong correlation with histological scores (r = -0.72, P < 0.001). ΔF max increased 2.6 times between a sound sealant margin and severe dye penetration. AUC analysis showed a high diagnostic accuracy of microleakage depth (AUC = 0.83–0.91). The AUC that differentiated the outer half microleakage of the sealant (histological score 0 vs 1–3) was the highest at 0.91. Conclusions The use of autofluorescence detection based on QLF technology enabled the detection of microleakages in sealants non-destructively and demonstrated excellent diagnostic validity." @default.
- W4386765443 created "2023-09-16" @default.
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- W4386765443 date "2023-09-15" @default.
- W4386765443 modified "2023-09-30" @default.
- W4386765443 title "Detection of pit and fissure sealant microleakage using autofluorescence" @default.
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- W4386765443 doi "https://doi.org/10.21203/rs.3.rs-3336538/v1" @default.
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