Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386767529> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W4386767529 endingPage "e0291572" @default.
- W4386767529 startingPage "e0291572" @default.
- W4386767529 abstract "We aimed to discover computationally-derived phenotypes of opioid-related patient presentations to the ED via clinical notes and structured electronic health record (EHR) data.This was a retrospective study of ED visits from 2013-2020 across ten sites within a regional healthcare network. We derived phenotypes from visits for patients ≥18 years of age with at least one prior or current documentation of an opioid-related diagnosis. Natural language processing was used to extract clinical entities from notes, which were combined with structured data within the EHR to create a set of features. We performed latent dirichlet allocation to identify topics within these features. Groups of patient presentations with similar attributes were identified by cluster analysis.In total 82,577 ED visits met inclusion criteria. The 30 topics were discovered ranging from those related to substance use disorder, chronic conditions, mental health, and medical management. Clustering on these topics identified nine unique cohorts with one-year survivals ranging from 84.2-96.8%, rates of one-year ED returns from 9-34%, rates of one-year opioid event 10-17%, rates of medications for opioid use disorder from 17-43%, and a median Carlson comorbidity index of 2-8. Two cohorts of phenotypes were identified related to chronic substance use disorder, or acute overdose.Our results indicate distinct phenotypic clusters with varying patient-oriented outcomes which provide future targets better allocation of resources and therapeutics. This highlights the heterogeneity of the overall population, and the need to develop targeted interventions for each population." @default.
- W4386767529 created "2023-09-16" @default.
- W4386767529 creator A5012426158 @default.
- W4386767529 creator A5019426692 @default.
- W4386767529 creator A5025601376 @default.
- W4386767529 creator A5026564301 @default.
- W4386767529 creator A5039268173 @default.
- W4386767529 creator A5048675944 @default.
- W4386767529 creator A5070252636 @default.
- W4386767529 creator A5071585624 @default.
- W4386767529 creator A5076431340 @default.
- W4386767529 creator A5079051180 @default.
- W4386767529 date "2023-09-15" @default.
- W4386767529 modified "2023-09-27" @default.
- W4386767529 title "Computational phenotypes for patients with opioid-related disorders presenting to the emergency department" @default.
- W4386767529 cites W2059796825 @default.
- W4386767529 cites W2067734229 @default.
- W4386767529 cites W2110548428 @default.
- W4386767529 cites W2131291880 @default.
- W4386767529 cites W2148477439 @default.
- W4386767529 cites W2341266170 @default.
- W4386767529 cites W2469750785 @default.
- W4386767529 cites W2608078055 @default.
- W4386767529 cites W2765305386 @default.
- W4386767529 cites W2805195258 @default.
- W4386767529 cites W2891469329 @default.
- W4386767529 cites W2897098357 @default.
- W4386767529 cites W2906355679 @default.
- W4386767529 cites W2941989738 @default.
- W4386767529 cites W2944133984 @default.
- W4386767529 cites W2951609968 @default.
- W4386767529 cites W2960642153 @default.
- W4386767529 cites W2982829304 @default.
- W4386767529 cites W3036644138 @default.
- W4386767529 cites W3128252805 @default.
- W4386767529 cites W3132147424 @default.
- W4386767529 cites W3158665049 @default.
- W4386767529 cites W3160915496 @default.
- W4386767529 cites W3202645141 @default.
- W4386767529 cites W3205104435 @default.
- W4386767529 cites W4206903838 @default.
- W4386767529 cites W4213196481 @default.
- W4386767529 cites W580496250 @default.
- W4386767529 doi "https://doi.org/10.1371/journal.pone.0291572" @default.
- W4386767529 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37713393" @default.
- W4386767529 hasPublicationYear "2023" @default.
- W4386767529 type Work @default.
- W4386767529 citedByCount "0" @default.
- W4386767529 crossrefType "journal-article" @default.
- W4386767529 hasAuthorship W4386767529A5012426158 @default.
- W4386767529 hasAuthorship W4386767529A5019426692 @default.
- W4386767529 hasAuthorship W4386767529A5025601376 @default.
- W4386767529 hasAuthorship W4386767529A5026564301 @default.
- W4386767529 hasAuthorship W4386767529A5039268173 @default.
- W4386767529 hasAuthorship W4386767529A5048675944 @default.
- W4386767529 hasAuthorship W4386767529A5070252636 @default.
- W4386767529 hasAuthorship W4386767529A5071585624 @default.
- W4386767529 hasAuthorship W4386767529A5076431340 @default.
- W4386767529 hasAuthorship W4386767529A5079051180 @default.
- W4386767529 hasBestOaLocation W43867675291 @default.
- W4386767529 hasConcept C118552586 @default.
- W4386767529 hasConcept C27415008 @default.
- W4386767529 hasConcept C2779159551 @default.
- W4386767529 hasConcept C2780724011 @default.
- W4386767529 hasConcept C2908647359 @default.
- W4386767529 hasConcept C40010229 @default.
- W4386767529 hasConcept C71924100 @default.
- W4386767529 hasConcept C99454951 @default.
- W4386767529 hasConceptScore W4386767529C118552586 @default.
- W4386767529 hasConceptScore W4386767529C27415008 @default.
- W4386767529 hasConceptScore W4386767529C2779159551 @default.
- W4386767529 hasConceptScore W4386767529C2780724011 @default.
- W4386767529 hasConceptScore W4386767529C2908647359 @default.
- W4386767529 hasConceptScore W4386767529C40010229 @default.
- W4386767529 hasConceptScore W4386767529C71924100 @default.
- W4386767529 hasConceptScore W4386767529C99454951 @default.
- W4386767529 hasFunder F4320337357 @default.
- W4386767529 hasFunder F4320338410 @default.
- W4386767529 hasIssue "9" @default.
- W4386767529 hasLocation W43867675291 @default.
- W4386767529 hasLocation W43867675292 @default.
- W4386767529 hasOpenAccess W4386767529 @default.
- W4386767529 hasPrimaryLocation W43867675291 @default.
- W4386767529 hasRelatedWork W2037156434 @default.
- W4386767529 hasRelatedWork W2054343004 @default.
- W4386767529 hasRelatedWork W2069534663 @default.
- W4386767529 hasRelatedWork W2073171214 @default.
- W4386767529 hasRelatedWork W2083673831 @default.
- W4386767529 hasRelatedWork W2143494072 @default.
- W4386767529 hasRelatedWork W2167076656 @default.
- W4386767529 hasRelatedWork W2168107350 @default.
- W4386767529 hasRelatedWork W2400381992 @default.
- W4386767529 hasRelatedWork W2772636962 @default.
- W4386767529 hasVolume "18" @default.
- W4386767529 isParatext "false" @default.
- W4386767529 isRetracted "false" @default.
- W4386767529 workType "article" @default.