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- W4386772241 abstract "This chapter describes the breakdown of lipids in the plasma membrane and the subsequent formation of messenger molecules that can transmit the signal(s) into the cell. It looks at the importance of the formation of new phosphorylated inositol lipids by phosphatidylinositol 3-kinase in many transduction events. The chapter also examines the inositol phosphates and highlights the inositol trisphosphate (InsP3) which may be the precursor of both higher and lower inositol phosphates, that is, it can be phosphorylated or dephosphorylated to create new metabolites, each of which may have a signalling role within the cell. Finally, the chapter analyses the role of diacylglycerol. Diacylglycerol (DAG) is known to act as an activator of protein kinase C. The chapter also reviews other lipid metabolism and several inositol phosphates which are thought to have defined signalling functions." @default.
- W4386772241 created "2023-09-16" @default.
- W4386772241 creator A5082543074 @default.
- W4386772241 date "2016-12-15" @default.
- W4386772241 modified "2023-09-27" @default.
- W4386772241 title "Inositol phosphate metabolism and roles of membrane lipids" @default.
- W4386772241 doi "https://doi.org/10.1093/hesc/9780199658480.003.0008" @default.
- W4386772241 hasPublicationYear "2016" @default.
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