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- W4386772562 abstract "This chapter reviews the human leucocyte antigens, the genes of which are found within the major histocompatibility complex (MHC), and how the detection and matching of the genes and gene products has contributed to the success of transplantation and the study of human disease. It begins by defining the Human Leucocyte Antigens (HLA) system. The chapter explores the role of the HLA system in transplantation and transfusion, then shows the principles of matching for haemopoietic stem cell transplantation, solid organ transplantation, and platelet transfusion. The chapter also studies the methods and technology for HLA typing and antibody testing used in the HLA laboratory. Finally, the chapter investigates the key immunological pathways targeted by immunosuppression, then looks at the hurdles to overcome in xenotransplantation." @default.
- W4386772562 created "2023-09-16" @default.
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- W4386772562 date "2018-04-19" @default.
- W4386772562 modified "2023-09-27" @default.
- W4386772562 title "Human Leucocyte Antigens (HLA) and Their Clinical Significance" @default.
- W4386772562 doi "https://doi.org/10.1093/hesc/9780198735731.003.0009" @default.
- W4386772562 hasPublicationYear "2018" @default.
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