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- W4386773481 abstract "This chapter talks about DNA replication, and it repairs and ties this topic to Charles Darwin’s concept of ‘descent with modification’, a fundamental principle of natural selection and evolution. It presents several challenges to DNA replication that arise from its length and anti-parallel structure, including the processes that have evolved to address these challenges. It also introduces the many types of mutation that occur, and how the occurrence of such mutations and the effects of selection can be revealed by comparing the genomes of different organisms. The chapter shows how to reconstruct evolutionary history and develop phylogenetic trees based on DNA sequence changes. It highlights the principle of descent with modification, which demonstrates the balance between two competing evolutionary pressures." @default.
- W4386773481 created "2023-09-16" @default.
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- W4386773481 date "2017-05-18" @default.
- W4386773481 modified "2023-09-27" @default.
- W4386773481 title "Descent with Modification: Continuity and Variation in the Genome" @default.
- W4386773481 doi "https://doi.org/10.1093/hesc/9780198712558.003.0005" @default.
- W4386773481 hasPublicationYear "2017" @default.
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