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- W4386774142 abstract "This chapter states that cell numbers in multicellular organisms are tightly regulated by the control of mitosis by mitogens and growth factors that stimulate cell division and growth and the genetically programmed death of damaged, diseased, or superfluous cells. It defines apoptosis as a highly regulated, genetically programmed process that eliminates unwanted, dysfunctional, or diseased cells by allowing them to self-degrade and die. It also mentions necrosis or accidental cell death, which can be caused by a chemical or physical assault to the cell or tissue. The chapter considers apoptosis as a natural part of the biology of multicellular organisms as it is involved in growth and development, maintaining homeostatic cell numbers, and eliminating cells that are diseased or have been damaged beyond repair. It looks at ways the balance in favour of apoptosis is induced, such as through certain types of physical or physiological stresses or lapses in the receipt of survival or trophic factors from other cells that prevent apoptosis." @default.
- W4386774142 created "2023-09-16" @default.
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- W4386774142 date "2013-02-21" @default.
- W4386774142 modified "2023-09-27" @default.
- W4386774142 title "Cell death" @default.
- W4386774142 doi "https://doi.org/10.1093/hesc/9780199697328.003.0017" @default.
- W4386774142 hasPublicationYear "2013" @default.
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