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- W4386779372 abstract "Copper is a microelement with important physiological functions in the body. However, the excess copper ion (Cu2+) may cause severe health problems, such as hair cell apoptosis and the resultant hearing loss. Therefore, the assay of Cu2+ is important. We integrate ionic imprinting technology (IIT) and structurally colored hydrogel beads to prepare chitosan-based ionically imprinted hydrogel beads (IIHBs) as a low-cost and high-specificity platform for Cu2+ detection. The IIHBs have a macroporous microstructure, uniform size, vivid structural color, and magnetic responsiveness. When incubated in solution, IIHBs recognize Cu2+ and exhibit a reflective peak change, thereby achieving label-free detection. In addition, benefiting from the IIT, the IIHBs display good specificity and selectivity and have an imprinting factor of 19.14 at 100 μmol∙L–1. These features indicated that the developed IIHBs are promising candidates for Cu2+ detection, particularly for the prevention of hearing loss." @default.
- W4386779372 created "2023-09-16" @default.
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- W4386779372 date "2023-09-01" @default.
- W4386779372 modified "2023-10-09" @default.
- W4386779372 title "Ionically Imprinting-Based Copper (Ⅱ) Label-Free Detection for Preventing Hearing Loss" @default.
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- W4386779372 doi "https://doi.org/10.1016/j.eng.2023.09.001" @default.
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