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- W4386783211 abstract "This chapter looks at how RNA molecules catalyse chemical reactions, a domain which was previously thought to be reserved only for proteins. It clarifies that RNA has a more limited set of functional groups for building catalysts, which are confined to just four different nucleotides: A, C, G, and U. It also highlights the ability of RNA molecules to form structures which also enables the assembly of RNA active sites. The chapter outlines the important function of metal ions in ribozymes, which includes helping RNA structures form and balance the strong negative charge in ribozyme active sites that result from high densities of RNA strands. It also mentions that the purine and pyrimidine bases of RNA have NH groups that can potentially act as hydrogen donors or acceptors in acid-base catalysis." @default.
- W4386783211 created "2023-09-16" @default.
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- W4386783211 date "2015-11-12" @default.
- W4386783211 modified "2023-09-27" @default.
- W4386783211 title "Catalytic RNAs" @default.
- W4386783211 doi "https://doi.org/10.1093/hesc/9780199671397.003.0003" @default.
- W4386783211 hasPublicationYear "2015" @default.
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