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- W4386783722 abstract "This chapter looks at autoimmune skin diseases such as pemphigoid and pemphigus. It notes how auto-antibodies are directed against protein at the dermal-epidermal junction in the pemphigoid, while pemphigus has auto-antibodies directed against cell junctions in the epidermis. The chapter indicates that specific auto-antibodies are associated with disruption of the skin structure leading to blistering. Biopsies or serums can demonstrate the presence of auto-antibodies as well. The chapter shows how treatment can include steroid, topic, systemic, steroid-sparing systemic immune suppression, high dose intravenous immunoglobulin, plasmapheresis in conjunction with systemic immune suppression, or monoclonal antibody therapy targeting B lymphocytes. In addition, it references other autoimmune blistering skin disorders such as dermatitis herpetiformis and toxic epidermal necrolysis." @default.
- W4386783722 created "2023-09-16" @default.
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- W4386783722 date "2016-03-10" @default.
- W4386783722 modified "2023-09-27" @default.
- W4386783722 title "Autoimmune skin disease" @default.
- W4386783722 doi "https://doi.org/10.1093/hesc/9780199657650.003.0008" @default.
- W4386783722 hasPublicationYear "2016" @default.
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