Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386803127> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W4386803127 abstract "We present a case report of a 54-year-old male with a metastatic testicular sex cord tumor harboring a EWSR1::ATF1 gene fusion. The tumor displayed a solid and nested architecture with sclerotic stroma and variable inflammatory infiltrate, and was positive for SF-1, inhibin, EMA, CD30, and WT1 expression. Further genetic analysis identified a EWSR1::ATF1 gene fusion. Overall findings were consistent with an inflammatory and nested testicular sex cord tumor, a recently described testicular neoplasm characterized by EWSR1::ATF1 gene fusion and aggressive clinical behavior. Due to the aggressive nature of this entity and the limited response to current treatment options available, identification of potential biomarkers for early diagnosis and targeted therapies are critical. This case report provides important insights into the genomic landscape of testicular sex cord-stromal tumors, especially within the CTNNB1-negative subset of patients with an aggressive clinical course, and further supports the distinction of inflammatory and nested testicular sex cord tumor as a separate entity from Sertoli cell tumors due to its characteristic morphological, immunohistochemical and molecular, features and clinical behavior." @default.
- W4386803127 created "2023-09-17" @default.
- W4386803127 creator A5025207573 @default.
- W4386803127 creator A5055845749 @default.
- W4386803127 creator A5064506130 @default.
- W4386803127 creator A5085695173 @default.
- W4386803127 date "2023-09-16" @default.
- W4386803127 modified "2023-09-26" @default.
- W4386803127 title "Metastatic Testicular Sex Cord Tumor Harboring a <i>EWSR1::ATF1</i> Gene Fusion—A Case Report of a Novel Neoplasm: “Inflammatory and Nested Testicular Sex Cord Tumor”" @default.
- W4386803127 cites W1970644296 @default.
- W4386803127 cites W1982319979 @default.
- W4386803127 cites W2003945247 @default.
- W4386803127 cites W2015003806 @default.
- W4386803127 cites W2057637200 @default.
- W4386803127 cites W2067259108 @default.
- W4386803127 cites W2088257020 @default.
- W4386803127 cites W2092289690 @default.
- W4386803127 cites W2096840271 @default.
- W4386803127 cites W2119244589 @default.
- W4386803127 cites W2160116126 @default.
- W4386803127 cites W2321952783 @default.
- W4386803127 cites W2509724820 @default.
- W4386803127 cites W2765224350 @default.
- W4386803127 cites W2771821139 @default.
- W4386803127 cites W3048135691 @default.
- W4386803127 cites W3166968358 @default.
- W4386803127 cites W3167738268 @default.
- W4386803127 cites W3172090161 @default.
- W4386803127 cites W3173473574 @default.
- W4386803127 cites W4281624741 @default.
- W4386803127 cites W4285678402 @default.
- W4386803127 cites W4298139025 @default.
- W4386803127 cites W4320895071 @default.
- W4386803127 doi "https://doi.org/10.1177/10668969231195043" @default.
- W4386803127 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37715645" @default.
- W4386803127 hasPublicationYear "2023" @default.
- W4386803127 type Work @default.
- W4386803127 citedByCount "0" @default.
- W4386803127 crossrefType "journal-article" @default.
- W4386803127 hasAuthorship W4386803127A5025207573 @default.
- W4386803127 hasAuthorship W4386803127A5055845749 @default.
- W4386803127 hasAuthorship W4386803127A5064506130 @default.
- W4386803127 hasAuthorship W4386803127A5085695173 @default.
- W4386803127 hasConcept C104317684 @default.
- W4386803127 hasConcept C111829193 @default.
- W4386803127 hasConcept C141071460 @default.
- W4386803127 hasConcept C142724271 @default.
- W4386803127 hasConcept C16930146 @default.
- W4386803127 hasConcept C204232928 @default.
- W4386803127 hasConcept C2779632786 @default.
- W4386803127 hasConcept C2780635560 @default.
- W4386803127 hasConcept C55493867 @default.
- W4386803127 hasConcept C71924100 @default.
- W4386803127 hasConcept C86803240 @default.
- W4386803127 hasConceptScore W4386803127C104317684 @default.
- W4386803127 hasConceptScore W4386803127C111829193 @default.
- W4386803127 hasConceptScore W4386803127C141071460 @default.
- W4386803127 hasConceptScore W4386803127C142724271 @default.
- W4386803127 hasConceptScore W4386803127C16930146 @default.
- W4386803127 hasConceptScore W4386803127C204232928 @default.
- W4386803127 hasConceptScore W4386803127C2779632786 @default.
- W4386803127 hasConceptScore W4386803127C2780635560 @default.
- W4386803127 hasConceptScore W4386803127C55493867 @default.
- W4386803127 hasConceptScore W4386803127C71924100 @default.
- W4386803127 hasConceptScore W4386803127C86803240 @default.
- W4386803127 hasLocation W43868031271 @default.
- W4386803127 hasLocation W43868031272 @default.
- W4386803127 hasOpenAccess W4386803127 @default.
- W4386803127 hasPrimaryLocation W43868031271 @default.
- W4386803127 hasRelatedWork W1984594523 @default.
- W4386803127 hasRelatedWork W2021173905 @default.
- W4386803127 hasRelatedWork W2055479802 @default.
- W4386803127 hasRelatedWork W2364913556 @default.
- W4386803127 hasRelatedWork W2364973444 @default.
- W4386803127 hasRelatedWork W2374617627 @default.
- W4386803127 hasRelatedWork W2390523857 @default.
- W4386803127 hasRelatedWork W2396770766 @default.
- W4386803127 hasRelatedWork W2405692590 @default.
- W4386803127 hasRelatedWork W3119807610 @default.
- W4386803127 isParatext "false" @default.
- W4386803127 isRetracted "false" @default.
- W4386803127 workType "article" @default.