Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386806824> ?p ?o ?g. }
- W4386806824 endingPage "133" @default.
- W4386806824 startingPage "126" @default.
- W4386806824 abstract "Immunotherapy has revolutionized cancer treatment with Chimeric Antigen Receptor (CAR) T cells and dendritic cell-based vaccines showing remarkable efficacy in certain malignancies. This review provides an integrative overview of recent advances and future directions in vaccinomics. A critical aspect of improving efficacy is the integration of CAR T cells and dendritic cell-based therapies to leverage synergistic effects. Personalization of cancer treatment, facilitated by strategies such as HLA typing and antigen selection, is essential for targeting specific tumor antigens and evading immune resistance. The tumor microenvironment plays a crucial role in modulating immune responses and can be targeted to enhance therapy efficacy. Novel adjuvants and immune modulators, such as Toll-like receptor agonists and checkpoint inhibitors, can further improve efficacy and safety. Predictive biomarkers and patient stratification strategies are essential for optimizing candidate selection. Future research should focus on optimizing CAR T cell and dendritic cell-based therapies, developing novel combinational strategies, and advancing gene editing and manufacturing techniques. Expansion to non-cancerous diseases could greatly broaden the impact on public health. Addressing challenges and limitations associated with these therapies can unlock their full potential and revolutionize the treatment of various malignancies and other medical conditions." @default.
- W4386806824 created "2023-09-17" @default.
- W4386806824 creator A5034502556 @default.
- W4386806824 date "2023-06-08" @default.
- W4386806824 modified "2023-09-27" @default.
- W4386806824 title "CAR T cells and dendritic cells: vaccinomics perspectives" @default.
- W4386806824 cites W1971821333 @default.
- W4386806824 cites W2001732035 @default.
- W4386806824 cites W2050216284 @default.
- W4386806824 cites W2066671159 @default.
- W4386806824 cites W2104904748 @default.
- W4386806824 cites W2112680373 @default.
- W4386806824 cites W2118796952 @default.
- W4386806824 cites W2122465970 @default.
- W4386806824 cites W2156840401 @default.
- W4386806824 cites W2258336271 @default.
- W4386806824 cites W2292411590 @default.
- W4386806824 cites W2322790172 @default.
- W4386806824 cites W2561499686 @default.
- W4386806824 cites W2566018578 @default.
- W4386806824 cites W2572491999 @default.
- W4386806824 cites W2738678436 @default.
- W4386806824 cites W2800948756 @default.
- W4386806824 cites W2807110328 @default.
- W4386806824 cites W2937946645 @default.
- W4386806824 cites W2946112461 @default.
- W4386806824 cites W2986629061 @default.
- W4386806824 cites W2987711192 @default.
- W4386806824 cites W2989957419 @default.
- W4386806824 cites W2992070886 @default.
- W4386806824 cites W2995764816 @default.
- W4386806824 cites W2998173997 @default.
- W4386806824 cites W2998881619 @default.
- W4386806824 cites W3007691816 @default.
- W4386806824 cites W3009601111 @default.
- W4386806824 cites W3010339454 @default.
- W4386806824 cites W3014146450 @default.
- W4386806824 cites W3014913757 @default.
- W4386806824 cites W3028523516 @default.
- W4386806824 cites W3033203711 @default.
- W4386806824 cites W3039484069 @default.
- W4386806824 cites W3040083476 @default.
- W4386806824 cites W3043154728 @default.
- W4386806824 cites W3045946240 @default.
- W4386806824 cites W3046025665 @default.
- W4386806824 cites W3068772833 @default.
- W4386806824 cites W3097803258 @default.
- W4386806824 cites W3108853735 @default.
- W4386806824 cites W3109851879 @default.
- W4386806824 cites W3113586980 @default.
- W4386806824 cites W3122008402 @default.
- W4386806824 cites W3122174179 @default.
- W4386806824 cites W3122235270 @default.
- W4386806824 cites W3124631812 @default.
- W4386806824 cites W3125073358 @default.
- W4386806824 cites W3129646946 @default.
- W4386806824 cites W3130791700 @default.
- W4386806824 cites W3134443156 @default.
- W4386806824 cites W3134454597 @default.
- W4386806824 cites W3135011427 @default.
- W4386806824 cites W3136653115 @default.
- W4386806824 cites W3137635187 @default.
- W4386806824 cites W3144140615 @default.
- W4386806824 cites W3148729173 @default.
- W4386806824 cites W3158029302 @default.
- W4386806824 cites W3160993535 @default.
- W4386806824 cites W3186173966 @default.
- W4386806824 cites W3192058068 @default.
- W4386806824 cites W3206428546 @default.
- W4386806824 cites W3208106660 @default.
- W4386806824 cites W4200424290 @default.
- W4386806824 cites W4205919871 @default.
- W4386806824 cites W4206977865 @default.
- W4386806824 cites W4212986801 @default.
- W4386806824 cites W4220775445 @default.
- W4386806824 cites W4226329559 @default.
- W4386806824 cites W4281393714 @default.
- W4386806824 cites W4281620351 @default.
- W4386806824 cites W4283644334 @default.
- W4386806824 cites W4283802230 @default.
- W4386806824 cites W4285594746 @default.
- W4386806824 cites W4286697597 @default.
- W4386806824 cites W4288427187 @default.
- W4386806824 cites W4289836155 @default.
- W4386806824 cites W4290841245 @default.
- W4386806824 cites W4292260448 @default.
- W4386806824 cites W4292846877 @default.
- W4386806824 cites W4293493284 @default.
- W4386806824 cites W4294679595 @default.
- W4386806824 cites W4296686974 @default.
- W4386806824 cites W4302304879 @default.
- W4386806824 cites W4306391391 @default.
- W4386806824 cites W4309593122 @default.
- W4386806824 cites W4309644024 @default.
- W4386806824 cites W4309883130 @default.
- W4386806824 cites W4311279974 @default.
- W4386806824 cites W4311986793 @default.
- W4386806824 cites W4312190528 @default.