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- W4386811544 endingPage "100361" @default.
- W4386811544 startingPage "100361" @default.
- W4386811544 abstract "Polysaccharides have attracted considerable attention as potential vehicles for drug delivery because of their unique and versatile characteristics. The biodegradability, biocompatibility, mucoadhesive characteristics, and tunable properties of polysaccharide make them attractive carriers for formulating of colon-targeted drug delivery systems. This review article encompasses the research on nanoparticles (NPs) based on polysaccharides (e. g. pectin, sodium alginate and chitosan) for targeted drug delivery to the colon. Various strategies such as microbially triggered, enzymatic degradation, and pH responsive systems have been discussed. Furthermore, ligand-based active targeting of therapeutics to colon has also been highlighted. The review also covers the various characterization and evaluation techniques used in the development of polysaccharide-based NPs. The importance of morphology, particle size (PS), surface charge of the NPs on performance of the delivery system has also been given due consideration. The challenges and future perspectives associated with colon drug delivery have been summarized. The information presented will be helpful to the scientific community when working with polysaccharides and will pave the way for improved therapeutic outcomes." @default.
- W4386811544 created "2023-09-18" @default.
- W4386811544 creator A5014194416 @default.
- W4386811544 creator A5033624278 @default.
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- W4386811544 creator A5067207161 @default.
- W4386811544 creator A5072329856 @default.
- W4386811544 creator A5083563852 @default.
- W4386811544 date "2023-12-01" @default.
- W4386811544 modified "2023-09-27" @default.
- W4386811544 title "Challenges, Opportunities, and Future Prospects of Polysaccharide-based Nanoparticles for Colon Targeting: A Comprehensive Review" @default.
- W4386811544 cites W1564553363 @default.
- W4386811544 cites W1971500643 @default.
- W4386811544 cites W1975530828 @default.
- W4386811544 cites W1977341513 @default.
- W4386811544 cites W1984056224 @default.
- W4386811544 cites W1990528707 @default.
- W4386811544 cites W1999592249 @default.
- W4386811544 cites W2001465846 @default.
- W4386811544 cites W2003610868 @default.
- W4386811544 cites W2010471774 @default.
- W4386811544 cites W2020168409 @default.
- W4386811544 cites W2022165935 @default.
- W4386811544 cites W2040557571 @default.
- W4386811544 cites W2045053498 @default.
- W4386811544 cites W2051925512 @default.
- W4386811544 cites W2056450557 @default.
- W4386811544 cites W2057945718 @default.
- W4386811544 cites W2063445996 @default.
- W4386811544 cites W2072018844 @default.
- W4386811544 cites W2074672324 @default.
- W4386811544 cites W2076580808 @default.
- W4386811544 cites W2089595610 @default.
- W4386811544 cites W2092201159 @default.
- W4386811544 cites W2108727062 @default.
- W4386811544 cites W2117630026 @default.
- W4386811544 cites W2121891676 @default.
- W4386811544 cites W2126765952 @default.
- W4386811544 cites W2170584001 @default.
- W4386811544 cites W2222895718 @default.
- W4386811544 cites W2266732512 @default.
- W4386811544 cites W2284960947 @default.
- W4386811544 cites W230458012 @default.
- W4386811544 cites W2316172829 @default.
- W4386811544 cites W2345335071 @default.
- W4386811544 cites W2463475103 @default.
- W4386811544 cites W2512924511 @default.
- W4386811544 cites W2528126207 @default.
- W4386811544 cites W2567863108 @default.
- W4386811544 cites W2596287086 @default.
- W4386811544 cites W2597688930 @default.
- W4386811544 cites W2597974214 @default.
- W4386811544 cites W2607888492 @default.
- W4386811544 cites W2736768972 @default.
- W4386811544 cites W2752133697 @default.
- W4386811544 cites W2757652705 @default.
- W4386811544 cites W2772268163 @default.
- W4386811544 cites W2785881131 @default.
- W4386811544 cites W2790865787 @default.
- W4386811544 cites W2797957695 @default.
- W4386811544 cites W2797986504 @default.
- W4386811544 cites W2799272514 @default.
- W4386811544 cites W2806033814 @default.
- W4386811544 cites W2818838409 @default.
- W4386811544 cites W2894875978 @default.
- W4386811544 cites W2898966205 @default.
- W4386811544 cites W2904891130 @default.
- W4386811544 cites W2908955335 @default.
- W4386811544 cites W2909584502 @default.
- W4386811544 cites W2913657934 @default.
- W4386811544 cites W2930104523 @default.
- W4386811544 cites W2934876677 @default.
- W4386811544 cites W2935095397 @default.
- W4386811544 cites W2949874704 @default.
- W4386811544 cites W2952025167 @default.
- W4386811544 cites W2973628697 @default.
- W4386811544 cites W2985235637 @default.
- W4386811544 cites W2988542752 @default.
- W4386811544 cites W2990834840 @default.
- W4386811544 cites W2996388828 @default.
- W4386811544 cites W2999590181 @default.
- W4386811544 cites W3000072346 @default.
- W4386811544 cites W3000884526 @default.
- W4386811544 cites W3001536676 @default.
- W4386811544 cites W3005510901 @default.
- W4386811544 cites W3005716572 @default.
- W4386811544 cites W3006629563 @default.
- W4386811544 cites W3006760893 @default.
- W4386811544 cites W3008652951 @default.
- W4386811544 cites W3009472917 @default.
- W4386811544 cites W3009894486 @default.
- W4386811544 cites W3022343152 @default.
- W4386811544 cites W3027988553 @default.
- W4386811544 cites W3033413755 @default.
- W4386811544 cites W3040741749 @default.
- W4386811544 cites W3041675208 @default.
- W4386811544 cites W3046601338 @default.