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- W4386814268 abstract "Airborne microplastics raise significant concerns due to their potential health impacts. Having a small size, larger surface area, and penetrative ability into the biological system, makes them hazardous to health. This review article compiles various studies investigating the mechanism of action of polystyrene micro- and nanoplastics affecting lung epithelial cells A549. These inhalable microplastics damage the respiratory system, by triggering a proinflammatory environment, genotoxicity, oxidative stress, morphological changes, and cytotoxic accumulation in A549 cells. PS-NP lung toxicity depends on various factors such as size, surface modifications, concentration, charge, and zeta potential. However, cellular uptake and cytotoxicity mechanisms depend on the cell type. For A549 cells, PS-NPs are responsible for energy imbalance by mitochondrial dysfunction, oxidative stress-mediated cytotoxicity, immunomodulation, and apoptosis. Additionally, PS-NPs have the ability to traverse the placental barrier, posing a risk to offspring. Despite the advancements, the precise mechanisms underlying how prolonged exposure to PS-NPs leads to the development and progression of lung diseases have unclear points, necessitating further investigations to unravel the root cause. This review also sheds light on data gaps, inconsistencies in PS-Nos research, and provides recommendations for further research in this field." @default.
- W4386814268 created "2023-09-18" @default.
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- W4386814268 date "2023-09-15" @default.
- W4386814268 modified "2023-10-17" @default.
- W4386814268 title "A549 as an In Vitro Model to Evaluate the Impact of Microplastics in the Air" @default.
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- W4386814268 cites W2115215892 @default.
- W4386814268 cites W2130962401 @default.
- W4386814268 cites W2132408764 @default.
- W4386814268 cites W2171437346 @default.
- W4386814268 cites W2176417723 @default.
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- W4386814268 doi "https://doi.org/10.3390/biology12091243" @default.
- W4386814268 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37759642" @default.
- W4386814268 hasPublicationYear "2023" @default.
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