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- W4386814453 endingPage "1167" @default.
- W4386814453 startingPage "1167" @default.
- W4386814453 abstract "Leptospirosis is a zoonotic disease of global importance with significant morbidity and mortality. However, the disease is frequently overlooked and underdiagnosed, leading to uncertainty of the true scale and severity of the disease. A neglected tropical disease, leptospirosis disproportionately impacts disadvantaged socioeconomic communities most vulnerable to outbreaks of zoonotic disease, due to contact with infectious animals and contaminated soils and waters. With growing evidence that Leptospira survives, persists, and reproduces in the environment, this paper reviews the current understanding of the pathogen in the environment and highlights the unknowns that are most important for future study. Through a systematic Boolean review of the literature, our study finds that detailed field-based study of Leptospira prevalence, survival, and transmission in natural waters and soils is lacking from the current literature. This review identified a strong need for assessment of physical characteristics and biogeochemical processes that support long-term viability of Leptospira in the environment followed by epidemiological assessment of the transmission and movement of the same strains of Leptospira in the present wildlife and livestock as the first steps in improving our understanding of the environmental stage of the leptospirosis transmission cycle." @default.
- W4386814453 created "2023-09-18" @default.
- W4386814453 creator A5046498667 @default.
- W4386814453 creator A5080179997 @default.
- W4386814453 date "2023-09-16" @default.
- W4386814453 modified "2023-10-17" @default.
- W4386814453 title "Leptospirosis and the Environment: A Review and Future Directions" @default.
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