FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386816320> ?p ?o ?g. }

• W4386816320 abstract "Mother-infant interactions during the early postnatal period are critical for infant survival and the scaffolding of infant development. Rodent models are used extensively to understand how these early social experiences influence neurobiology across the lifespan. However, methods for measuring postnatal dam-pup interactions typically involve time-consuming manual scoring, vary widely between research groups, and produce low density data that limits downstream analytical applications. To address these methodological issues, we developed the Automated Maternal Behavior during Early life in Rodents (AMBER) pipeline for quantifying home-cage maternal and mother-pup interactions using open-source machine learning tools. DeepLabCut was used to track key points on rat dams (32 points) and individual pups (9 points per pup) in postnatal day 1-10 video recordings. Pose estimation models reached test errors of 14.39 pixels and 11.81 pixels for dam and pups respectively. Pose estimation data and human-annotated behavior labels from 30 videos were used with Simple Behavioral Analysis (SimBA) to generate behavior classifiers for dam active nursing, passive nursing, nest attendance, licking and grooming, self-directed grooming, eating, and drinking using random forest algorithms. All classifiers had excellent performance, with F1 scores above .997. A set of 242 videos was used with AMBER and produced behavior measures in the expected range from postnatal 1-10 home-cage videos. This pipeline provides a basis for assessing home-cage dam-pup interactions that reduces experimenter burden while increasing reproducibility, reliability, and detail of data for use in developmental studies without the need for special housing systems or proprietary software." @default.
• W4386816320 created "2023-09-18" @default.
• W4386816320 creator A5020016338 @default.
• W4386816320 creator A5024946293 @default.
• W4386816320 creator A5026147565 @default.
• W4386816320 date "2023-09-16" @default.
• W4386816320 modified "2023-10-18" @default.
• W4386816320 title "Automated Maternal Behavior during Early life in Rodents (AMBER) pipeline" @default.
• W4386816320 cites W1706529635 @default.
• W4386816320 cites W1938688077 @default.
• W4386816320 cites W1951724000 @default.
• W4386816320 cites W1974200821 @default.
• W4386816320 cites W1996643069 @default.
• W4386816320 cites W1998980503 @default.
• W4386816320 cites W2011718521 @default.
• W4386816320 cites W2019265717 @default.
• W4386816320 cites W2020269446 @default.
• W4386816320 cites W2054692302 @default.
• W4386816320 cites W2066171961 @default.
• W4386816320 cites W2073047972 @default.
• W4386816320 cites W2076115217 @default.
• W4386816320 cites W2079612872 @default.
• W4386816320 cites W2086751914 @default.
• W4386816320 cites W2087368034 @default.
• W4386816320 cites W2100209152 @default.
• W4386816320 cites W2110374066 @default.
• W4386816320 cites W2119333871 @default.
• W4386816320 cites W2126858369 @default.
• W4386816320 cites W2136007792 @default.
• W4386816320 cites W2137189178 @default.
• W4386816320 cites W2154723612 @default.
• W4386816320 cites W2178837340 @default.
• W4386816320 cites W2291581860 @default.
• W4386816320 cites W2346578806 @default.
• W4386816320 cites W2604015016 @default.
• W4386816320 cites W2887114371 @default.
• W4386816320 cites W2913341725 @default.
• W4386816320 cites W2951349638 @default.
• W4386816320 cites W2980030724 @default.
• W4386816320 cites W2999615587 @default.
• W4386816320 cites W3016904080 @default.
• W4386816320 cites W3037927687 @default.
• W4386816320 cites W3087056597 @default.
• W4386816320 cites W3159833820 @default.
• W4386816320 cites W4224443987 @default.
• W4386816320 cites W4283328541 @default.
• W4386816320 cites W4298142861 @default.
• W4386816320 cites W815062328 @default.
• W4386816320 doi "https://doi.org/10.1101/2023.09.15.557946" @default.
• W4386816320 hasPublicationYear "2023" @default.
• W4386816320 type Work @default.
• W4386816320 citedByCount "0" @default.
• W4386816320 crossrefType "posted-content" @default.
• W4386816320 hasAuthorship W4386816320A5020016338 @default.
• W4386816320 hasAuthorship W4386816320A5024946293 @default.
• W4386816320 hasAuthorship W4386816320A5026147565 @default.
• W4386816320 hasBestOaLocation W43868163201 @default.
• W4386816320 hasConcept C119857082 @default.
• W4386816320 hasConcept C138496976 @default.
• W4386816320 hasConcept C154945302 @default.
• W4386816320 hasConcept C15744967 @default.
• W4386816320 hasConcept C2780723003 @default.
• W4386816320 hasConcept C41008148 @default.
• W4386816320 hasConcept C71924100 @default.
• W4386816320 hasConcept C98274493 @default.
• W4386816320 hasConceptScore W4386816320C119857082 @default.
• W4386816320 hasConceptScore W4386816320C138496976 @default.
• W4386816320 hasConceptScore W4386816320C154945302 @default.
• W4386816320 hasConceptScore W4386816320C15744967 @default.
• W4386816320 hasConceptScore W4386816320C2780723003 @default.
• W4386816320 hasConceptScore W4386816320C41008148 @default.
• W4386816320 hasConceptScore W4386816320C71924100 @default.
• W4386816320 hasConceptScore W4386816320C98274493 @default.
• W4386816320 hasLocation W43868163201 @default.
• W4386816320 hasOpenAccess W4386816320 @default.
• W4386816320 hasPrimaryLocation W43868163201 @default.
• W4386816320 hasRelatedWork W2961085424 @default.
• W4386816320 hasRelatedWork W3046775127 @default.
• W4386816320 hasRelatedWork W3107602296 @default.
• W4386816320 hasRelatedWork W3170094116 @default.
• W4386816320 hasRelatedWork W3209574120 @default.
• W4386816320 hasRelatedWork W4210805261 @default.
• W4386816320 hasRelatedWork W4306674287 @default.
• W4386816320 hasRelatedWork W4312192474 @default.
• W4386816320 hasRelatedWork W4386462264 @default.
• W4386816320 hasRelatedWork W4387297750 @default.
• W4386816320 isParatext "false" @default.
• W4386816320 isRetracted "false" @default.
• W4386816320 workType "article" @default.