Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386817823> ?p ?o ?g. }
- W4386817823 endingPage "44688" @default.
- W4386817823 startingPage "44676" @default.
- W4386817823 abstract "Postoperative intrauterine adhesion (IUA), caused by endometrial basal layer injury, is one of the main causes of female infertility. The excessive deposition of fibrin as well as fibroblast is considered the root cause of IUA. However, few clinical strategies are effective in preventing extracellular matrix (ECM) deposition at endometrial wounds that include protein and cell deposits. Herein, the injectable granular poly(N-(2-hydroxyethyl) acrylamide) (PHEAA) hydrogel (granular PHEAA gel), which presents excellent antifouling properties and remarkably prevents protein and cell adhesions, is used to prevent postoperative IUA. The granular PHEAA gel with a jammed network structure exhibits outstanding injectability and superior stability. Compared with the IUA group, the granular PHEAA gel can promote regeneration of the endometrium while reducing the area of endometrial fibrosis. Immunohistochemical staining experiments indicate that the granular PHEAA gel can improve the proliferation of the endometrium, promote vascularization, and enhance anti-inflammatory effect in IUA rats. And the granular PHEAA gel can effectively slow down the fibrosis of uterine tissue. Importantly, the number of embryos is significantly increased after injecting granular PHEAA gel, inferring that there is an obvious reproductive function recovery of injured endometrium." @default.
- W4386817823 created "2023-09-19" @default.
- W4386817823 creator A5002630915 @default.
- W4386817823 creator A5011004554 @default.
- W4386817823 creator A5018349171 @default.
- W4386817823 creator A5019056174 @default.
- W4386817823 creator A5025483246 @default.
- W4386817823 creator A5044388938 @default.
- W4386817823 creator A5054314125 @default.
- W4386817823 creator A5063501555 @default.
- W4386817823 creator A5082350583 @default.
- W4386817823 creator A5090243438 @default.
- W4386817823 date "2023-09-18" @default.
- W4386817823 modified "2023-10-13" @default.
- W4386817823 title "Antifouling and Injectable Granular Hydrogel for the Prevention of Postoperative Intrauterine Adhesion" @default.
- W4386817823 cites W2006256853 @default.
- W4386817823 cites W2029046412 @default.
- W4386817823 cites W2029132903 @default.
- W4386817823 cites W2031106320 @default.
- W4386817823 cites W2048808551 @default.
- W4386817823 cites W2463801883 @default.
- W4386817823 cites W2464633546 @default.
- W4386817823 cites W2609203566 @default.
- W4386817823 cites W2688834197 @default.
- W4386817823 cites W2741863801 @default.
- W4386817823 cites W2760284529 @default.
- W4386817823 cites W2798122587 @default.
- W4386817823 cites W2900486389 @default.
- W4386817823 cites W2946891466 @default.
- W4386817823 cites W2947917992 @default.
- W4386817823 cites W2993622027 @default.
- W4386817823 cites W3011639188 @default.
- W4386817823 cites W3028348313 @default.
- W4386817823 cites W3043335930 @default.
- W4386817823 cites W3046989607 @default.
- W4386817823 cites W3088221067 @default.
- W4386817823 cites W3094232321 @default.
- W4386817823 cites W3115763040 @default.
- W4386817823 cites W3119477232 @default.
- W4386817823 cites W3127214104 @default.
- W4386817823 cites W3128632705 @default.
- W4386817823 cites W3132304297 @default.
- W4386817823 cites W3133717155 @default.
- W4386817823 cites W3138935227 @default.
- W4386817823 cites W3182713146 @default.
- W4386817823 cites W3203291236 @default.
- W4386817823 cites W3206546416 @default.
- W4386817823 cites W3210044804 @default.
- W4386817823 cites W3217739719 @default.
- W4386817823 cites W4200318567 @default.
- W4386817823 cites W4200479914 @default.
- W4386817823 cites W4206907634 @default.
- W4386817823 cites W4210811925 @default.
- W4386817823 cites W4212836971 @default.
- W4386817823 cites W4220707212 @default.
- W4386817823 cites W4224939617 @default.
- W4386817823 cites W4285499044 @default.
- W4386817823 cites W4293325638 @default.
- W4386817823 cites W4294679597 @default.
- W4386817823 cites W4308774833 @default.
- W4386817823 cites W4313562076 @default.
- W4386817823 cites W4320032925 @default.
- W4386817823 cites W4323318954 @default.
- W4386817823 cites W4323533341 @default.
- W4386817823 cites W4367322822 @default.
- W4386817823 cites W4375856554 @default.
- W4386817823 doi "https://doi.org/10.1021/acsami.3c07846" @default.
- W4386817823 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37721504" @default.
- W4386817823 hasPublicationYear "2023" @default.
- W4386817823 type Work @default.
- W4386817823 citedByCount "0" @default.
- W4386817823 crossrefType "journal-article" @default.
- W4386817823 hasAuthorship W4386817823A5002630915 @default.
- W4386817823 hasAuthorship W4386817823A5011004554 @default.
- W4386817823 hasAuthorship W4386817823A5018349171 @default.
- W4386817823 hasAuthorship W4386817823A5019056174 @default.
- W4386817823 hasAuthorship W4386817823A5025483246 @default.
- W4386817823 hasAuthorship W4386817823A5044388938 @default.
- W4386817823 hasAuthorship W4386817823A5054314125 @default.
- W4386817823 hasAuthorship W4386817823A5063501555 @default.
- W4386817823 hasAuthorship W4386817823A5082350583 @default.
- W4386817823 hasAuthorship W4386817823A5090243438 @default.
- W4386817823 hasConcept C126322002 @default.
- W4386817823 hasConcept C142724271 @default.
- W4386817823 hasConcept C159985019 @default.
- W4386817823 hasConcept C185592680 @default.
- W4386817823 hasConcept C189165786 @default.
- W4386817823 hasConcept C192562407 @default.
- W4386817823 hasConcept C202751555 @default.
- W4386817823 hasConcept C2779742232 @default.
- W4386817823 hasConcept C2780381497 @default.
- W4386817823 hasConcept C2780559512 @default.
- W4386817823 hasConcept C55493867 @default.
- W4386817823 hasConcept C71924100 @default.
- W4386817823 hasConcept C84416704 @default.
- W4386817823 hasConcept C86803240 @default.
- W4386817823 hasConcept C95444343 @default.
- W4386817823 hasConceptScore W4386817823C126322002 @default.