Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386820361> ?p ?o ?g. }
Showing items 1 to 61 of
61
with 100 items per page.
- W4386820361 abstract "Cervical cancer presents a significant global health concern with high-risk human papilloma-viruses (HPVs) being identified as the cause of this cancer. Although current treatment methods for cervical cancer can eliminate lesions, preventing metastatic spread and minimizing tissue damage remains a major challenge. Therefore, the development of a safer and innovative thera-peutic approach is of utmost importance. Natural products like Fig latex, derived from the Ficus Carica tree, have demonstrated promising anti-cancer properties when tested on cervical cancer cell lines. However, the specific mechanisms by which Fig latex exerts its effects are still un-known. In this study, we conducted RNA-seq analysis to explore how Fig latex may counteract carcinogenesis in HPV-positive cervical cancer cell lines, namely CaSki (HPV type 16-positive) and HeLa (HPV type 18-positive). Our data from this investigation indicates that Fig latex influ-ences the expression of genes associated with the development and progression of cervical can-cer, including pathways related to " Nonsense-Mediated Decay (NMD) "cell cycle regulation" and Transcriptional Regulation by TP53. This selective impact of Fig latex on cancer-related pathways suggests a potential novel therapeutic approach for HPV-related cervical cancer." @default.
- W4386820361 created "2023-09-19" @default.
- W4386820361 creator A5002123209 @default.
- W4386820361 creator A5014070729 @default.
- W4386820361 creator A5058435984 @default.
- W4386820361 creator A5085190579 @default.
- W4386820361 date "2023-09-18" @default.
- W4386820361 modified "2023-09-26" @default.
- W4386820361 title "Gene Expression Analysis Reveals the Regulatory Effect of <em>Ficus carica</em> Latex on Cell Cycle Progression in Human Papillomavirus Positive Cervical Cancer Cell Lines" @default.
- W4386820361 doi "https://doi.org/10.20944/preprints202309.1172.v1" @default.
- W4386820361 hasPublicationYear "2023" @default.
- W4386820361 type Work @default.
- W4386820361 citedByCount "0" @default.
- W4386820361 crossrefType "posted-content" @default.
- W4386820361 hasAuthorship W4386820361A5002123209 @default.
- W4386820361 hasAuthorship W4386820361A5014070729 @default.
- W4386820361 hasAuthorship W4386820361A5058435984 @default.
- W4386820361 hasAuthorship W4386820361A5085190579 @default.
- W4386820361 hasBestOaLocation W43868203611 @default.
- W4386820361 hasConcept C121608353 @default.
- W4386820361 hasConcept C1491633281 @default.
- W4386820361 hasConcept C2777366897 @default.
- W4386820361 hasConcept C2778220009 @default.
- W4386820361 hasConcept C2779231358 @default.
- W4386820361 hasConcept C2779362140 @default.
- W4386820361 hasConcept C29537977 @default.
- W4386820361 hasConcept C502942594 @default.
- W4386820361 hasConcept C54355233 @default.
- W4386820361 hasConcept C555283112 @default.
- W4386820361 hasConcept C59822182 @default.
- W4386820361 hasConcept C71924100 @default.
- W4386820361 hasConcept C86803240 @default.
- W4386820361 hasConceptScore W4386820361C121608353 @default.
- W4386820361 hasConceptScore W4386820361C1491633281 @default.
- W4386820361 hasConceptScore W4386820361C2777366897 @default.
- W4386820361 hasConceptScore W4386820361C2778220009 @default.
- W4386820361 hasConceptScore W4386820361C2779231358 @default.
- W4386820361 hasConceptScore W4386820361C2779362140 @default.
- W4386820361 hasConceptScore W4386820361C29537977 @default.
- W4386820361 hasConceptScore W4386820361C502942594 @default.
- W4386820361 hasConceptScore W4386820361C54355233 @default.
- W4386820361 hasConceptScore W4386820361C555283112 @default.
- W4386820361 hasConceptScore W4386820361C59822182 @default.
- W4386820361 hasConceptScore W4386820361C71924100 @default.
- W4386820361 hasConceptScore W4386820361C86803240 @default.
- W4386820361 hasLocation W43868203611 @default.
- W4386820361 hasOpenAccess W4386820361 @default.
- W4386820361 hasPrimaryLocation W43868203611 @default.
- W4386820361 hasRelatedWork W1562891572 @default.
- W4386820361 hasRelatedWork W2082805292 @default.
- W4386820361 hasRelatedWork W2114101456 @default.
- W4386820361 hasRelatedWork W2115542424 @default.
- W4386820361 hasRelatedWork W2273401678 @default.
- W4386820361 hasRelatedWork W2374614804 @default.
- W4386820361 hasRelatedWork W2386797884 @default.
- W4386820361 hasRelatedWork W2390328034 @default.
- W4386820361 hasRelatedWork W3135282863 @default.
- W4386820361 hasRelatedWork W3165304082 @default.
- W4386820361 isParatext "false" @default.
- W4386820361 isRetracted "false" @default.
- W4386820361 workType "article" @default.