Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386827467> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W4386827467 abstract "Even though many of the approved drugs still have high systemic toxicity due to a lack of tumor selectivity and present pharmacokinetic drawbacks, like low water solubility, that negatively influence the drug circulation time and bioavailability, the anti-cancer study has produced commendable results in recent years. The stability tests carried out under stressful exposure to high temperatures, hydrolytic media, or light sources during their development or under moderate settings have shown the vulnerability of anti-cancer medications to various factors. Because of this, the development of degradation products is considered hospital waste in pharmaceutical formulations and the environment. Until now, various formulations have been created for attaining tissue-specific therapeutic targeting, lowering harmful side effects, and enhancing drug stability. To boost the specificity, efficiency, and durability of active molecules that are targeted in cancer therapy the invention of prodrugs is the potential approach. The latest study illustrates that the solubility, pharmacokinetics, cellular uptake, and stability of chemotherapy drugs can be improved through the incorporation of them into vesicular systems, such as polymeric micelles or cyclodextrins, or via nanocarriers containing chemotherapeutics linked to monoclonal antibodies. In this review article, we provide an overview of the most recent advances in the field of designing very stable prodrugs or nanosystems that are powerful anti-cancer medications and their actions on the body." @default.
- W4386827467 created "2023-09-19" @default.
- W4386827467 creator A5020662301 @default.
- W4386827467 creator A5044114421 @default.
- W4386827467 creator A5057787180 @default.
- W4386827467 creator A5066125366 @default.
- W4386827467 creator A5092894536 @default.
- W4386827467 date "2023-09-18" @default.
- W4386827467 modified "2023-09-26" @default.
- W4386827467 title "Novel Chemotherapy Modalities for Different Cancers" @default.
- W4386827467 cites W1246937494 @default.
- W4386827467 cites W1440506460 @default.
- W4386827467 cites W1981587077 @default.
- W4386827467 cites W1996474536 @default.
- W4386827467 cites W2003814325 @default.
- W4386827467 cites W2014058353 @default.
- W4386827467 cites W2024607307 @default.
- W4386827467 cites W2056716232 @default.
- W4386827467 cites W2107710830 @default.
- W4386827467 cites W2109079185 @default.
- W4386827467 cites W2110216592 @default.
- W4386827467 cites W2198521858 @default.
- W4386827467 cites W2279561773 @default.
- W4386827467 cites W2341461271 @default.
- W4386827467 cites W2422216916 @default.
- W4386827467 cites W2514623573 @default.
- W4386827467 cites W2528228811 @default.
- W4386827467 cites W2564938142 @default.
- W4386827467 cites W2607355358 @default.
- W4386827467 cites W2805302875 @default.
- W4386827467 cites W2913584903 @default.
- W4386827467 cites W2917113139 @default.
- W4386827467 cites W2947826965 @default.
- W4386827467 cites W2975141952 @default.
- W4386827467 cites W2976192812 @default.
- W4386827467 cites W2990602894 @default.
- W4386827467 cites W2996630100 @default.
- W4386827467 cites W2996703666 @default.
- W4386827467 cites W3013347515 @default.
- W4386827467 cites W3111470573 @default.
- W4386827467 cites W3114344131 @default.
- W4386827467 cites W3135098376 @default.
- W4386827467 cites W3148729173 @default.
- W4386827467 cites W3201749743 @default.
- W4386827467 cites W4220909053 @default.
- W4386827467 cites W4226051140 @default.
- W4386827467 cites W4323668013 @default.
- W4386827467 doi "https://doi.org/10.7759/cureus.45474" @default.
- W4386827467 hasPublicationYear "2023" @default.
- W4386827467 type Work @default.
- W4386827467 citedByCount "0" @default.
- W4386827467 crossrefType "journal-article" @default.
- W4386827467 hasAuthorship W4386827467A5020662301 @default.
- W4386827467 hasAuthorship W4386827467A5044114421 @default.
- W4386827467 hasAuthorship W4386827467A5057787180 @default.
- W4386827467 hasAuthorship W4386827467A5066125366 @default.
- W4386827467 hasAuthorship W4386827467A5092894536 @default.
- W4386827467 hasBestOaLocation W43868274671 @default.
- W4386827467 hasConcept C108215921 @default.
- W4386827467 hasConcept C112705442 @default.
- W4386827467 hasConcept C121608353 @default.
- W4386827467 hasConcept C126322002 @default.
- W4386827467 hasConcept C181389837 @default.
- W4386827467 hasConcept C18150654 @default.
- W4386827467 hasConcept C2776694085 @default.
- W4386827467 hasConcept C2777899217 @default.
- W4386827467 hasConcept C2778971682 @default.
- W4386827467 hasConcept C2780035454 @default.
- W4386827467 hasConcept C2780192828 @default.
- W4386827467 hasConcept C71924100 @default.
- W4386827467 hasConcept C98274493 @default.
- W4386827467 hasConceptScore W4386827467C108215921 @default.
- W4386827467 hasConceptScore W4386827467C112705442 @default.
- W4386827467 hasConceptScore W4386827467C121608353 @default.
- W4386827467 hasConceptScore W4386827467C126322002 @default.
- W4386827467 hasConceptScore W4386827467C181389837 @default.
- W4386827467 hasConceptScore W4386827467C18150654 @default.
- W4386827467 hasConceptScore W4386827467C2776694085 @default.
- W4386827467 hasConceptScore W4386827467C2777899217 @default.
- W4386827467 hasConceptScore W4386827467C2778971682 @default.
- W4386827467 hasConceptScore W4386827467C2780035454 @default.
- W4386827467 hasConceptScore W4386827467C2780192828 @default.
- W4386827467 hasConceptScore W4386827467C71924100 @default.
- W4386827467 hasConceptScore W4386827467C98274493 @default.
- W4386827467 hasLocation W43868274671 @default.
- W4386827467 hasOpenAccess W4386827467 @default.
- W4386827467 hasPrimaryLocation W43868274671 @default.
- W4386827467 hasRelatedWork W1796348015 @default.
- W4386827467 hasRelatedWork W1970331292 @default.
- W4386827467 hasRelatedWork W2080955156 @default.
- W4386827467 hasRelatedWork W2086700810 @default.
- W4386827467 hasRelatedWork W2279554812 @default.
- W4386827467 hasRelatedWork W2317627837 @default.
- W4386827467 hasRelatedWork W2400119402 @default.
- W4386827467 hasRelatedWork W2606334551 @default.
- W4386827467 hasRelatedWork W3023756610 @default.
- W4386827467 hasRelatedWork W88005891 @default.
- W4386827467 isParatext "false" @default.
- W4386827467 isRetracted "false" @default.
- W4386827467 workType "article" @default.