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- W4386829096 abstract "The invention in this patent application relates to 4-aminopyridazin-6-one derivatives represented generally by formula 1. These compounds are inhibitors of the NOD-like receptor protein 3 (NLRP3) inflammasome pathway and may potentially provide a useful treatment for one or more of the diseases and disorders mediated by NLRP3, including but not limited to immune diseases, inflammatory diseases, autoimmune diseases, autoinflammatory fever syndromes, cryopyrin-associated periodic syndrome, chronic liver disease, kidney-related disease, hyperoxaluria, lupus nephritis, Type I and Type II diabetes, nephropathy, neurodegenerative diseases, Alzheimer’s disease, cardiovascular diseases, metabolic diseases and many more." @default.
- W4386829096 created "2023-09-19" @default.
- W4386829096 creator A5044951316 @default.
- W4386829096 date "2023-09-18" @default.
- W4386829096 modified "2023-09-26" @default.
- W4386829096 title "The Potential of NOD-like Receptor Protein 3 Inflammasome Inhibitors in the Treatments of Diseases" @default.
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- W4386829096 doi "https://doi.org/10.1021/acsmedchemlett.3c00378" @default.
- W4386829096 hasPublicationYear "2023" @default.
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