FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386837142> ?p ?o ?g. }

• W4386837142 endingPage "658" @default.
• W4386837142 startingPage "639" @default.
• W4386837142 abstract "The understanding of granule growth mechanisms and the effects of formulation and operating conditions over product quality and process performance in fluidized bed co-melt granulation is nowadays of great interest. In this sense, this work systematically studies the combined effects of binder content (WPEG) and fluidization air flowrate (FA) and temperature (TA) on granules’ quality and process-related variables (product mass (MP), elutriated fines (Mf), mass stuck on walls (MW)) by using a Box–Behnken-type design of experiments (DoE), as it is a statistical tool suggested by the Quality by Design (QbD) initiative. It was found that the granules’ size and powder flowability are significantly affected by WPEG (higher WPEG, higher granule size and better flowability). Interestingly, TA is the process variable that significantly affects MP, enhancing process performance at high temperature values. Regarding FA, it significantly affects d10, promoting the formation of small particles due to breakage at high flowrates and the presence of non-elutriated powder at low flowrates. As a consequence, intermediate FA is the optimum for obtaining higher MP. Regarding regime map studies, most runs experienced a rapid growth regime, which is in accordance with the granules’ high pore saturation. This result agrees with the observed high increment in particle size and the morphology of the final granules, allowing researchers to validate and extend existing previous maps." @default.
• W4386837142 created "2023-09-19" @default.
• W4386837142 creator A5012874113 @default.
• W4386837142 creator A5053486869 @default.
• W4386837142 creator A5092896708 @default.
• W4386837142 date "2023-09-15" @default.
• W4386837142 modified "2023-09-26" @default.
• W4386837142 title "Fluidized Bed Co-Melt Granulation: New Insights in the Influence of Process Variables and Validation of Regime Map Theory" @default.
• W4386837142 cites W1882987386 @default.
• W4386837142 cites W1965141078 @default.
• W4386837142 cites W1976339028 @default.
• W4386837142 cites W1976656565 @default.
• W4386837142 cites W1978031983 @default.
• W4386837142 cites W1980078794 @default.
• W4386837142 cites W1986681016 @default.
• W4386837142 cites W1994839339 @default.
• W4386837142 cites W1995424208 @default.
• W4386837142 cites W1996311220 @default.
• W4386837142 cites W2002085046 @default.
• W4386837142 cites W2003726932 @default.
• W4386837142 cites W2021609753 @default.
• W4386837142 cites W2022473768 @default.
• W4386837142 cites W2039917267 @default.
• W4386837142 cites W2046321719 @default.
• W4386837142 cites W2050495458 @default.
• W4386837142 cites W2055423026 @default.
• W4386837142 cites W2059674132 @default.
• W4386837142 cites W2072839437 @default.
• W4386837142 cites W2082612023 @default.
• W4386837142 cites W2124151679 @default.
• W4386837142 cites W2149589571 @default.
• W4386837142 cites W2774521502 @default.
• W4386837142 cites W2790995736 @default.
• W4386837142 cites W2904797069 @default.
• W4386837142 cites W3043674023 @default.
• W4386837142 cites W4241073798 @default.
• W4386837142 doi "https://doi.org/10.3390/powders2030040" @default.
• W4386837142 hasPublicationYear "2023" @default.
• W4386837142 type Work @default.
• W4386837142 citedByCount "0" @default.
• W4386837142 crossrefType "journal-article" @default.
• W4386837142 hasAuthorship W4386837142A5012874113 @default.
• W4386837142 hasAuthorship W4386837142A5053486869 @default.
• W4386837142 hasAuthorship W4386837142A5092896708 @default.
• W4386837142 hasBestOaLocation W43868371421 @default.
• W4386837142 hasConcept C105795698 @default.
• W4386837142 hasConcept C114614502 @default.
• W4386837142 hasConcept C116628846 @default.
• W4386837142 hasConcept C121332964 @default.
• W4386837142 hasConcept C127413603 @default.
• W4386837142 hasConcept C150077022 @default.
• W4386837142 hasConcept C159985019 @default.
• W4386837142 hasConcept C170295934 @default.
• W4386837142 hasConcept C185592680 @default.
• W4386837142 hasConcept C187530423 @default.
• W4386837142 hasConcept C192562407 @default.
• W4386837142 hasConcept C194832619 @default.
• W4386837142 hasConcept C2084832 @default.
• W4386837142 hasConcept C21880701 @default.
• W4386837142 hasConcept C2779015675 @default.
• W4386837142 hasConcept C33923547 @default.
• W4386837142 hasConcept C34559072 @default.
• W4386837142 hasConcept C42360764 @default.
• W4386837142 hasConcept C43617362 @default.
• W4386837142 hasConcept C49760210 @default.
• W4386837142 hasConcept C548081761 @default.
• W4386837142 hasConcept C57879066 @default.
• W4386837142 hasConcept C75892298 @default.
• W4386837142 hasConcept C88463166 @default.
• W4386837142 hasConcept C9930424 @default.
• W4386837142 hasConceptScore W4386837142C105795698 @default.
• W4386837142 hasConceptScore W4386837142C114614502 @default.
• W4386837142 hasConceptScore W4386837142C116628846 @default.
• W4386837142 hasConceptScore W4386837142C121332964 @default.
• W4386837142 hasConceptScore W4386837142C127413603 @default.
• W4386837142 hasConceptScore W4386837142C150077022 @default.
• W4386837142 hasConceptScore W4386837142C159985019 @default.
• W4386837142 hasConceptScore W4386837142C170295934 @default.
• W4386837142 hasConceptScore W4386837142C185592680 @default.
• W4386837142 hasConceptScore W4386837142C187530423 @default.
• W4386837142 hasConceptScore W4386837142C192562407 @default.
• W4386837142 hasConceptScore W4386837142C194832619 @default.
• W4386837142 hasConceptScore W4386837142C2084832 @default.
• W4386837142 hasConceptScore W4386837142C21880701 @default.
• W4386837142 hasConceptScore W4386837142C2779015675 @default.
• W4386837142 hasConceptScore W4386837142C33923547 @default.
• W4386837142 hasConceptScore W4386837142C34559072 @default.
• W4386837142 hasConceptScore W4386837142C42360764 @default.
• W4386837142 hasConceptScore W4386837142C43617362 @default.
• W4386837142 hasConceptScore W4386837142C49760210 @default.
• W4386837142 hasConceptScore W4386837142C548081761 @default.
• W4386837142 hasConceptScore W4386837142C57879066 @default.
• W4386837142 hasConceptScore W4386837142C75892298 @default.
• W4386837142 hasConceptScore W4386837142C88463166 @default.
• W4386837142 hasConceptScore W4386837142C9930424 @default.
• W4386837142 hasFunder F4320323402 @default.
• W4386837142 hasFunder F4320334832 @default.
• W4386837142 hasIssue "3" @default.

• next