FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386838559> ?p ?o ?g. }

• W4386838559 abstract "Objective Some salivary proteins seem to be differently abundant among caries-free (CF) and caries-affected (CA) individuals, but previous results are contradictory precluding that definitive conclusion be drawn. A pooled analysis of the available evidence may provide more robust data on identifying oral cavity protein patterns among CF and CA individuals. This systematic review and meta-analysis (PROSPERO CRD42021269079) aimed to compare the oral cavity protein abundance among caries-free and caries-affected individuals. Methods This study was conducted following PRISMA guidelines. PubMed, Embase, and Web of Science databases were systematically assessed (up to February 2023) to retrieve clinical studies written in English, German, or in Latin-based languages that compared the oral cavity protein abundance among CF and CA individuals. Data extraction and methodological quality assessment (NIH guidelines) were independently performed by two investigators. Qualitative synthesis was performed from all included studies and meta-analysis was performed using a random-effects model with inverse variance for studies that reported the concentration of proteins or enzymatic activity. Standardized mean difference (SMD) with respective 95% confidence interval (CI) were calculated for each outcome. Results A total of 90 studies (two cohort and 88 cross-sectional designs) of more than 6,000 participants were selected for data extraction, being the quality of evidence graded as “fair” for most of them. The oral cavity of CF individuals presented lower total protein concentration [SMD = 0.37 (95% CI: 0.07–0.68; 18 studies)], lower total antioxidant capacity [SMD = 1.29 (95% CI: 0.74–1.85); 17 studies], and lower carbonic anhydrase activity [SMD = 0.83 (95% CI: 0.58–1.09); three studies], whereas CA individuals presented lower carbonic anhydrase concentration [SMD = −0.66 (95% CI: −1.00 to −0.32); three studies], urease [SMD = −0.95 (IC 95%: −1.72 to −0.17); four studies], and arginine deiminase system [SMD = −2.07 (95% CI: −3.53 to −0.62); three studies] activities. Antimicrobial peptides, secretory immunoglobulin-A concentrations and alpha-amylase activity were similar among individuals. Conclusion Differences on oral cavity protein abundance were observed among CF and CA individuals. These data indicate some protein patterns for the oral health and dental caries conditions. Even when statistically significant, some of the results were not very consistent. Cohort studies need to be conducted to validate these results." @default.
• W4386838559 created "2023-09-19" @default.
• W4386838559 creator A5014934437 @default.
• W4386838559 creator A5017557085 @default.
• W4386838559 creator A5067174143 @default.
• W4386838559 creator A5085701942 @default.
• W4386838559 date "2023-09-15" @default.
• W4386838559 modified "2023-10-05" @default.
• W4386838559 title "Comparison of oral cavity protein abundance among caries-free and caries-affected individuals—a systematic review and meta-analysis" @default.
• W4386838559 cites W1511646128 @default.
• W4386838559 cites W1586040773 @default.
• W4386838559 cites W1597603121 @default.
• W4386838559 cites W1641045756 @default.
• W4386838559 cites W1704664557 @default.
• W4386838559 cites W1768056945 @default.
• W4386838559 cites W1789142572 @default.
• W4386838559 cites W1803814887 @default.
• W4386838559 cites W1831390617 @default.
• W4386838559 cites W1889821241 @default.
• W4386838559 cites W1927179939 @default.
• W4386838559 cites W1934037969 @default.
• W4386838559 cites W1967039103 @default.
• W4386838559 cites W1968259246 @default.
• W4386838559 cites W1970348612 @default.
• W4386838559 cites W1970531656 @default.
• W4386838559 cites W1971322021 @default.
• W4386838559 cites W1972676270 @default.
• W4386838559 cites W1975067992 @default.
• W4386838559 cites W1975239472 @default.
• W4386838559 cites W1979635849 @default.
• W4386838559 cites W1981766973 @default.
• W4386838559 cites W1982220955 @default.
• W4386838559 cites W1986980325 @default.
• W4386838559 cites W1994648268 @default.
• W4386838559 cites W1996006776 @default.
• W4386838559 cites W2001593241 @default.
• W4386838559 cites W2002549311 @default.
• W4386838559 cites W2007074844 @default.
• W4386838559 cites W2007866195 @default.
• W4386838559 cites W2013303462 @default.
• W4386838559 cites W2016234249 @default.
• W4386838559 cites W2020213039 @default.
• W4386838559 cites W2025051880 @default.
• W4386838559 cites W2030434248 @default.
• W4386838559 cites W2040385059 @default.
• W4386838559 cites W2041816457 @default.
• W4386838559 cites W2044102142 @default.
• W4386838559 cites W2050605074 @default.
• W4386838559 cites W2052586849 @default.
• W4386838559 cites W2059197095 @default.
• W4386838559 cites W2061906147 @default.
• W4386838559 cites W2062190892 @default.
• W4386838559 cites W2063688578 @default.
• W4386838559 cites W2064086266 @default.
• W4386838559 cites W2069168915 @default.
• W4386838559 cites W2071164896 @default.
• W4386838559 cites W2074352991 @default.
• W4386838559 cites W2077025202 @default.
• W4386838559 cites W2088989040 @default.
• W4386838559 cites W2090687085 @default.
• W4386838559 cites W2091614238 @default.
• W4386838559 cites W2091719063 @default.
• W4386838559 cites W2094586801 @default.
• W4386838559 cites W2098561534 @default.
• W4386838559 cites W2104934425 @default.
• W4386838559 cites W2107971163 @default.
• W4386838559 cites W2111923715 @default.
• W4386838559 cites W2116558722 @default.
• W4386838559 cites W2118246788 @default.
• W4386838559 cites W2121522554 @default.
• W4386838559 cites W2123053539 @default.
• W4386838559 cites W2129744517 @default.
• W4386838559 cites W2137522692 @default.
• W4386838559 cites W2142603308 @default.
• W4386838559 cites W2143213141 @default.
• W4386838559 cites W2143276181 @default.
• W4386838559 cites W2152978370 @default.
• W4386838559 cites W2158847998 @default.
• W4386838559 cites W2160485370 @default.
• W4386838559 cites W2160977062 @default.
• W4386838559 cites W2163863205 @default.
• W4386838559 cites W2168472975 @default.
• W4386838559 cites W2169836613 @default.
• W4386838559 cites W2170529714 @default.
• W4386838559 cites W2176586445 @default.
• W4386838559 cites W2176803826 @default.
• W4386838559 cites W2183004675 @default.
• W4386838559 cites W2191438094 @default.
• W4386838559 cites W2196541738 @default.
• W4386838559 cites W2202049815 @default.
• W4386838559 cites W2240034653 @default.
• W4386838559 cites W2296832809 @default.
• W4386838559 cites W2298917682 @default.
• W4386838559 cites W2365731019 @default.
• W4386838559 cites W2410447756 @default.
• W4386838559 cites W2419032540 @default.
• W4386838559 cites W2479112886 @default.
• W4386838559 cites W2494737845 @default.
• W4386838559 cites W2501268296 @default.
• W4386838559 cites W2580466901 @default.

• next