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- W4386844239 abstract "Abstract Ethical animal use follows the 3R’s: reduction, reuse and replacement. Here we present the use of simultaneous jugular vein and cisterna magna catheterization with a port system in rats for repeated fluid sampling for 14 consecutive days without losing catheter patency. This technique allows repeated intra-animal sampling and if used with pooling samples from a cohort of animals, replaces the need for terminal collections for sufficient sample volumes." @default.
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- W4386844239 date "2023-09-19" @default.
- W4386844239 modified "2023-09-27" @default.
- W4386844239 title "A technique for repeated blood and cerebrospinal fluid sampling from individual rats over time without the need for repeated anaesthesia" @default.
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- W4386844239 doi "https://doi.org/10.21203/rs.3.rs-3332481/v1" @default.
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