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- W4386852079 endingPage "105219" @default.
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- W4386852079 abstract "Human parainfluenza viruses (HPIVs) are a leading cause of acute respiratory tract infections (ARTIs). Non-pharmaceutical interventions (NPIs) were widely administered to combat the pandemic of the coronavirus disease 2019 (COVID-19). Respiratory specimens were obtained from 10454 hospitalized children with ARTIs to detect HPIV. We investigated differences in epidemiological and clinical characteristics of HPIV infections before (2017–2019) and during the COVID-19 pandemic (2020–2022). HPIVs were detected in 392 (3.75%, 392/10454) patients, of whom 70 (17.86%), 48 (12.24%), and 274 (69.90%) were positive for HPIV1, HPIV2, and HPIV3, respectively. Detection rates of HPIV3 were higher in 2020–2022 than in 2017–2019 (3.38% vs. 2.24%). The seasonal distribution of HPIV1 showed no difference, but HPIV3 peaked between September and December during the COVID-19 pandemic, which differed from previous epidemiological patterns. Compared to the period before the COVID-19 pandemic, there has been a noticeable decrease in the incidence of asthma, moist rales, and emesis in patients infected with HPIV1 and in asthma, expectoration, and severe pneumonia in patients infected with HPIV3 during 2020–2022. The detection rates of HPIV increased in Southern China during the COVID-19 outbreak, which underlines the importance of continuous surveillance of HPIV in the next epidemic season." @default.
- W4386852079 created "2023-09-20" @default.
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- W4386852079 date "2023-11-01" @default.
- W4386852079 modified "2023-09-30" @default.
- W4386852079 title "Clinical impact of human parainfluenza virus infections before and during the COVID-19 pandemic in Southern China" @default.
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- W4386852079 doi "https://doi.org/10.1016/j.micinf.2023.105219" @default.
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