FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386854030> ?p ?o ?g. }

• W4386854030 endingPage "045011" @default.
• W4386854030 startingPage "045011" @default.
• W4386854030 abstract "Photo-induced dark transient states of fluorophores can pose a problem in fluorescence spectroscopy. However, their typically long lifetimes also make them highly environment sensitive, suggesting fluorophores with prominent dark-state formation yields to be used as microenvironmental sensors in bio-molecular spectroscopy and imaging. In this work, we analyzed the singlet-triplet transitions of fluorescein and three synthesized carboxy-fluorescein derivatives, with one, two or four bromines linked to the anthracence backbone. Using transient state (TRAST) spectroscopy, we found a prominent internal heavy atom (IHA) enhancement of the intersystem crossing (ISC) rates upon bromination, inferred by density functional theory calculations to take place via a higher triplet state, followed by relaxation to the lowest triplet state. A corresponding external heavy atom (EHA) enhancement was found upon adding potassium iodide (KI). Notably, increased KI concentrations still resulted in lowered triplet state buildup in the brominated fluorophores, due to relatively lower enhancements in ISC, than in the triplet decay. Together with an antioxidative effect on the fluorophores, adding KI thus generated a fluorescence enhancement of the brominated fluorophores. By TRAST measurements, analyzing the average fluorescence intensity of fluorescent molecules subject to a systematically varied excitation modulation, dark state transitions within very high triplet yield (>90%) fluorophores can be directly analyzed under biologically relevant conditions. These measurements, not possible by other techniques such as fluorescence correlation spectroscopy, opens for bio-sensing applications based on high triplet yield fluorophores, and for characterization of high triplet yield photodynamic therapy agents, and how they are influenced by IHA and EHA effects." @default.
• W4386854030 created "2023-09-20" @default.
• W4386854030 creator A5001903731 @default.
• W4386854030 creator A5013002722 @default.
• W4386854030 creator A5025699533 @default.
• W4386854030 creator A5053665869 @default.
• W4386854030 creator A5072409817 @default.
• W4386854030 creator A5089142147 @default.
• W4386854030 date "2023-10-01" @default.
• W4386854030 modified "2023-10-06" @default.
• W4386854030 title "Photo-physical characterization of high triplet yield brominated fluoresceins by transient state (TRAST) spectroscopy" @default.
• W4386854030 cites W1496968590 @default.
• W4386854030 cites W1507739119 @default.
• W4386854030 cites W1973948015 @default.
• W4386854030 cites W1976786825 @default.
• W4386854030 cites W1977502222 @default.
• W4386854030 cites W1986578141 @default.
• W4386854030 cites W1994149778 @default.
• W4386854030 cites W2002173240 @default.
• W4386854030 cites W2005918551 @default.
• W4386854030 cites W2012379620 @default.
• W4386854030 cites W2021877333 @default.
• W4386854030 cites W2022922186 @default.
• W4386854030 cites W2049126768 @default.
• W4386854030 cites W2050636876 @default.
• W4386854030 cites W2068998399 @default.
• W4386854030 cites W2070879521 @default.
• W4386854030 cites W2078857483 @default.
• W4386854030 cites W2091433403 @default.
• W4386854030 cites W2117561934 @default.
• W4386854030 cites W2125763400 @default.
• W4386854030 cites W2157456092 @default.
• W4386854030 cites W2165548215 @default.
• W4386854030 cites W2538315435 @default.
• W4386854030 cites W2594822719 @default.
• W4386854030 cites W2770434908 @default.
• W4386854030 cites W2970154091 @default.
• W4386854030 cites W2980996914 @default.
• W4386854030 cites W2991565823 @default.
• W4386854030 cites W3023047955 @default.
• W4386854030 cites W3049042348 @default.
• W4386854030 cites W3167778171 @default.
• W4386854030 cites W4210814026 @default.
• W4386854030 cites W4223925042 @default.
• W4386854030 cites W4250600349 @default.
• W4386854030 doi "https://doi.org/10.1088/2050-6120/acfb59" @default.
• W4386854030 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37726005" @default.
• W4386854030 hasPublicationYear "2023" @default.
• W4386854030 type Work @default.
• W4386854030 citedByCount "0" @default.
• W4386854030 crossrefType "journal-article" @default.
• W4386854030 hasAuthorship W4386854030A5001903731 @default.
• W4386854030 hasAuthorship W4386854030A5013002722 @default.
• W4386854030 hasAuthorship W4386854030A5025699533 @default.
• W4386854030 hasAuthorship W4386854030A5053665869 @default.
• W4386854030 hasAuthorship W4386854030A5072409817 @default.
• W4386854030 hasAuthorship W4386854030A5089142147 @default.
• W4386854030 hasBestOaLocation W43868540301 @default.
• W4386854030 hasConcept C120665830 @default.
• W4386854030 hasConcept C121332964 @default.
• W4386854030 hasConcept C134121241 @default.
• W4386854030 hasConcept C158711907 @default.
• W4386854030 hasConcept C171001562 @default.
• W4386854030 hasConcept C178790620 @default.
• W4386854030 hasConcept C181500209 @default.
• W4386854030 hasConcept C184779094 @default.
• W4386854030 hasConcept C185592680 @default.
• W4386854030 hasConcept C191897082 @default.
• W4386854030 hasConcept C192562407 @default.
• W4386854030 hasConcept C32891209 @default.
• W4386854030 hasConcept C32909587 @default.
• W4386854030 hasConcept C33062035 @default.
• W4386854030 hasConcept C62520636 @default.
• W4386854030 hasConcept C73978554 @default.
• W4386854030 hasConcept C75473681 @default.
• W4386854030 hasConcept C76766466 @default.
• W4386854030 hasConcept C91881484 @default.
• W4386854030 hasConceptScore W4386854030C120665830 @default.
• W4386854030 hasConceptScore W4386854030C121332964 @default.
• W4386854030 hasConceptScore W4386854030C134121241 @default.
• W4386854030 hasConceptScore W4386854030C158711907 @default.
• W4386854030 hasConceptScore W4386854030C171001562 @default.
• W4386854030 hasConceptScore W4386854030C178790620 @default.
• W4386854030 hasConceptScore W4386854030C181500209 @default.
• W4386854030 hasConceptScore W4386854030C184779094 @default.
• W4386854030 hasConceptScore W4386854030C185592680 @default.
• W4386854030 hasConceptScore W4386854030C191897082 @default.
• W4386854030 hasConceptScore W4386854030C192562407 @default.
• W4386854030 hasConceptScore W4386854030C32891209 @default.
• W4386854030 hasConceptScore W4386854030C32909587 @default.
• W4386854030 hasConceptScore W4386854030C33062035 @default.
• W4386854030 hasConceptScore W4386854030C62520636 @default.
• W4386854030 hasConceptScore W4386854030C73978554 @default.
• W4386854030 hasConceptScore W4386854030C75473681 @default.
• W4386854030 hasConceptScore W4386854030C76766466 @default.
• W4386854030 hasConceptScore W4386854030C91881484 @default.
• W4386854030 hasFunder F4320322581 @default.
• W4386854030 hasIssue "4" @default.

• next