Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386860057> ?p ?o ?g. }
- W4386860057 endingPage "14796" @default.
- W4386860057 startingPage "14787" @default.
- W4386860057 abstract "Discriminatively visualizing mitochondrial and lysosomal dysfunction is crucial for an in-depth understanding of cell apoptosis regulation and relative biology. However, fluorescent probes for the separate visualization of lysosomal and mitochondria damages have not been reported yet. Herein, we have constructed a fluorescent probe [2-(4-hydroxystyryl)-1,3,3-trimethyl-3H-indol-1-ium iodide (HBSI)] for labeling mitochondria and lysosomes in dual emission colors and discriminatively imaging mitochondrial and lysosomal damage in two different sets of fluorescent signals. In living cells, HBSI targeted both lysosomes and mitochondria to give green and red emission, respectively. During mitochondrial damages, HBSI immigrated into lysosomes, and the red emission decreased. During lysosomal damage, HBSI immigrated into mitochondria, and the green emission decreased. With the robust probe, the different damaging sequences of mitochondria and lysosomes under different amounts of H2O2 and chloral hydrate have been revealed. The sequential damage of lysosomes and mitochondria during cell apoptosis induced by rotenone, paclitaxel, and colchicine has been discovered. Furthermore, the regulation of mitochondria, lysosome, and their interplay during autophagy was also observed with the probe." @default.
- W4386860057 created "2023-09-20" @default.
- W4386860057 creator A5005075703 @default.
- W4386860057 creator A5028458322 @default.
- W4386860057 creator A5037583694 @default.
- W4386860057 creator A5040920162 @default.
- W4386860057 creator A5045510538 @default.
- W4386860057 creator A5078104183 @default.
- W4386860057 date "2023-09-19" @default.
- W4386860057 modified "2023-10-16" @default.
- W4386860057 title "Construction of a Dual-Emissive Probe for Discriminative Visualization of Lysosomal and Mitochondrial Dysfunction" @default.
- W4386860057 cites W1548851567 @default.
- W4386860057 cites W1766184155 @default.
- W4386860057 cites W1972708772 @default.
- W4386860057 cites W1980638751 @default.
- W4386860057 cites W2005139390 @default.
- W4386860057 cites W2015015357 @default.
- W4386860057 cites W2017593971 @default.
- W4386860057 cites W2033448006 @default.
- W4386860057 cites W2034773856 @default.
- W4386860057 cites W2075008758 @default.
- W4386860057 cites W2080878773 @default.
- W4386860057 cites W2090456613 @default.
- W4386860057 cites W2113999599 @default.
- W4386860057 cites W2138948114 @default.
- W4386860057 cites W2141416399 @default.
- W4386860057 cites W2154747925 @default.
- W4386860057 cites W2156241187 @default.
- W4386860057 cites W2320213632 @default.
- W4386860057 cites W2336416528 @default.
- W4386860057 cites W2587851416 @default.
- W4386860057 cites W2604116219 @default.
- W4386860057 cites W2788432017 @default.
- W4386860057 cites W2899093059 @default.
- W4386860057 cites W2929961692 @default.
- W4386860057 cites W2940953002 @default.
- W4386860057 cites W2963014728 @default.
- W4386860057 cites W3004905553 @default.
- W4386860057 cites W3127083694 @default.
- W4386860057 cites W3196397927 @default.
- W4386860057 cites W3211843398 @default.
- W4386860057 cites W4205196039 @default.
- W4386860057 cites W4220852797 @default.
- W4386860057 cites W4234505218 @default.
- W4386860057 cites W4245236624 @default.
- W4386860057 cites W4255124627 @default.
- W4386860057 cites W4324026882 @default.
- W4386860057 cites W4366079460 @default.
- W4386860057 cites W4377990545 @default.
- W4386860057 doi "https://doi.org/10.1021/acs.analchem.3c03024" @default.
- W4386860057 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37726214" @default.
- W4386860057 hasPublicationYear "2023" @default.
- W4386860057 type Work @default.
- W4386860057 citedByCount "0" @default.
- W4386860057 crossrefType "journal-article" @default.
- W4386860057 hasAuthorship W4386860057A5005075703 @default.
- W4386860057 hasAuthorship W4386860057A5028458322 @default.
- W4386860057 hasAuthorship W4386860057A5037583694 @default.
- W4386860057 hasAuthorship W4386860057A5040920162 @default.
- W4386860057 hasAuthorship W4386860057A5045510538 @default.
- W4386860057 hasAuthorship W4386860057A5078104183 @default.
- W4386860057 hasConcept C121332964 @default.
- W4386860057 hasConcept C12554922 @default.
- W4386860057 hasConcept C168240541 @default.
- W4386860057 hasConcept C181199279 @default.
- W4386860057 hasConcept C185592680 @default.
- W4386860057 hasConcept C190283241 @default.
- W4386860057 hasConcept C203522944 @default.
- W4386860057 hasConcept C2780216420 @default.
- W4386860057 hasConcept C28859421 @default.
- W4386860057 hasConcept C55493867 @default.
- W4386860057 hasConcept C62520636 @default.
- W4386860057 hasConcept C86803240 @default.
- W4386860057 hasConcept C91881484 @default.
- W4386860057 hasConcept C95444343 @default.
- W4386860057 hasConceptScore W4386860057C121332964 @default.
- W4386860057 hasConceptScore W4386860057C12554922 @default.
- W4386860057 hasConceptScore W4386860057C168240541 @default.
- W4386860057 hasConceptScore W4386860057C181199279 @default.
- W4386860057 hasConceptScore W4386860057C185592680 @default.
- W4386860057 hasConceptScore W4386860057C190283241 @default.
- W4386860057 hasConceptScore W4386860057C203522944 @default.
- W4386860057 hasConceptScore W4386860057C2780216420 @default.
- W4386860057 hasConceptScore W4386860057C28859421 @default.
- W4386860057 hasConceptScore W4386860057C55493867 @default.
- W4386860057 hasConceptScore W4386860057C62520636 @default.
- W4386860057 hasConceptScore W4386860057C86803240 @default.
- W4386860057 hasConceptScore W4386860057C91881484 @default.
- W4386860057 hasConceptScore W4386860057C95444343 @default.
- W4386860057 hasFunder F4320321001 @default.
- W4386860057 hasFunder F4320324174 @default.
- W4386860057 hasIssue "39" @default.
- W4386860057 hasLocation W43868600571 @default.
- W4386860057 hasLocation W43868600572 @default.
- W4386860057 hasOpenAccess W4386860057 @default.
- W4386860057 hasPrimaryLocation W43868600571 @default.
- W4386860057 hasRelatedWork W1975460873 @default.
- W4386860057 hasRelatedWork W1985200273 @default.