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• W4386860827 abstract "Abstract Background Patients with inflammatory bowel disease (IBD) are at higher risk for severe COVID-19 infection. However, most studies are single-center, and nationwide data in the United States are lacking. This study aimed to investigate hospital-related outcomes and predictors of these outcomes in patients with IBD and COVID-19 infection. Methods The National Inpatient Sample and National Readmission database were queried for all the patient hospitalizations with IBD with concurrent COVID-19 in the study group and non-COVID-19 related hospitalizations in the control group. For patients under 18 years, elective and trauma-related hospitalizations were excluded. Primary outcomes included mortality, septic shock, mechanical ventilation, and intensive care utilization. Secondary outcomes included length of stay and total hospitalization costs. Results From this query, 8865 adult patients with IBD and COVID-19 were identified. These patients were relatively older (62.8 vs 57.7 years, P &lt; .01), and the majority were females (52.1% with COVID-19 vs 55.2% without COVID-19). Patients with IBD and COVID-19 had higher mortality (12.24% vs 2.55%; P &lt; .01), increased incidence of septic shock (7.9% vs 4.4%; P &lt; .01), mechanical ventilation (11.5% vs 3.7%; P &lt; .01), and intensive care utilization (12% vs 4.6%; P &lt; .01). These patients also had higher mean length of stay (8.28 days vs 5.47 days; P &lt; .01) and total hospitalization costs ($21 390 vs $16 468; P &lt; .01) than those without COVID-19 infection. Conclusions Patients with IBD and COVID-19 have worse outcomes, with a higher incidence of severe COVID-19 disease, leading to higher mortality rates, longer lengths of stay, and increased total hospitalization costs. Encouraging preventive health measures and treating promptly with advanced COVID-19 therapies may improve outcomes and decrease the healthcare burden." @default.
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• W4386860827 date "2023-09-19" @default.
• W4386860827 modified "2023-10-18" @default.
• W4386860827 title "Predictors of Hospital-related Outcomes of COVID-19 Infection in Patients With Inflammatory Bowel Disease in the Early Pandemic Phase: A Nationwide Inpatient Database Survey" @default.
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• W4386860827 doi "https://doi.org/10.1093/ibd/izad200" @default.
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