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• W4386864583 abstract "In this study, we present the first spatial transcriptomic atlas of Atlantic salmon skin using the Visium Spatial Gene Expression protocol. We utilized frozen skin tissue from four distinct sites, namely the operculum, pectoral and caudal fins, and scaly skin at the flank of the fish close to the lateral line, obtained from two Atlantic salmon (150 g). High quality frozen tissue sections were obtained by embedding tissue in O.C.T media prior to freezing and sectioning. Further, we generated libraries and spatial transcriptomic maps, achieving a minimum of 80 million reads per sample with mapping efficiencies ranging from 79.3% to 89.4%. Our analysis revealed the detection of over 80.000 transcripts and nearly 30.000 genes in each sample. Among the tissue types observed in the skin, the epithelial tissues exhibited the highest number of transcripts (UMI-counts), followed by muscle tissue, loose and fibrous connective tissue, and bone. Notably, the widest nodes in the transcriptome network were shared among the epithelial clusters, while dermal tissues showed less consistency, which is likely attributable to the presence of multiple cell types at different body locations. Additionally, we identified collagen type 1 as the most prominent gene family in the skin, while keratins were found to be abundant in the epithelial tissue. Furthermore, we successfully identified gene markers specific to epithelial tissue, bone, and mesenchyme. To validate their expression patterns, we conducted a meta-analysis of the microarray database, which confirmed high expression levels of these markers in mucosal organs, skin, gills, and the olfactory rosette." @default.
• W4386864583 created "2023-09-20" @default.
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• W4386864583 date "2023-09-19" @default.
• W4386864583 modified "2023-10-09" @default.
• W4386864583 title "Transcriptomic landscape of Atlantic salmon (<i>Salmo salar</i> L.) skin" @default.
• W4386864583 cites W1511399689 @default.
• W4386864583 cites W1539441748 @default.
• W4386864583 cites W1809465273 @default.
• W4386864583 cites W1830558689 @default.
• W4386864583 cites W1849234135 @default.
• W4386864583 cites W1877885392 @default.
• W4386864583 cites W1968261842 @default.
• W4386864583 cites W1977361006 @default.
• W4386864583 cites W1979033746 @default.
• W4386864583 cites W1979686755 @default.
• W4386864583 cites W1985840227 @default.
• W4386864583 cites W1987926928 @default.
• W4386864583 cites W1989608676 @default.
• W4386864583 cites W2018354161 @default.
• W4386864583 cites W2021113636 @default.
• W4386864583 cites W2034175657 @default.
• W4386864583 cites W2041986831 @default.
• W4386864583 cites W2042343633 @default.
• W4386864583 cites W2047756488 @default.
• W4386864583 cites W2050890162 @default.
• W4386864583 cites W2051769832 @default.
• W4386864583 cites W2059032249 @default.
• W4386864583 cites W2060698810 @default.
• W4386864583 cites W2064233919 @default.
• W4386864583 cites W2069089843 @default.
• W4386864583 cites W2071411643 @default.
• W4386864583 cites W2073049453 @default.
• W4386864583 cites W2083457899 @default.
• W4386864583 cites W2086620837 @default.
• W4386864583 cites W2090813767 @default.
• W4386864583 cites W2093526323 @default.
• W4386864583 cites W2095498253 @default.
• W4386864583 cites W2104051134 @default.
• W4386864583 cites W2112858189 @default.
• W4386864583 cites W2126000047 @default.
• W4386864583 cites W2129149353 @default.
• W4386864583 cites W2132346528 @default.
• W4386864583 cites W2150315498 @default.
• W4386864583 cites W2285081944 @default.
• W4386864583 cites W2329880895 @default.
• W4386864583 cites W2337283254 @default.
• W4386864583 cites W2343169334 @default.
• W4386864583 cites W2345733750 @default.
• W4386864583 cites W2471536144 @default.
• W4386864583 cites W2524734072 @default.
• W4386864583 cites W2536088032 @default.
• W4386864583 cites W2616483049 @default.
• W4386864583 cites W2753871481 @default.
• W4386864583 cites W2775768612 @default.
• W4386864583 cites W2783986954 @default.
• W4386864583 cites W2789288433 @default.
• W4386864583 cites W2870819341 @default.
• W4386864583 cites W2899821960 @default.
• W4386864583 cites W2919888255 @default.
• W4386864583 cites W2955338790 @default.
• W4386864583 cites W2964340384 @default.
• W4386864583 cites W2970872110 @default.
• W4386864583 cites W2972025315 @default.
• W4386864583 cites W2995703197 @default.
• W4386864583 cites W3016703378 @default.
• W4386864583 cites W3023701177 @default.
• W4386864583 cites W3031672647 @default.
• W4386864583 cites W3049343495 @default.
• W4386864583 cites W3089289366 @default.
• W4386864583 cites W3092391984 @default.
• W4386864583 cites W3098211275 @default.
• W4386864583 cites W3122524957 @default.
• W4386864583 cites W3152183034 @default.
• W4386864583 cites W3154164150 @default.
• W4386864583 cites W3179474363 @default.
• W4386864583 cites W4206542402 @default.
• W4386864583 cites W4211012770 @default.
• W4386864583 cites W4211257929 @default.
• W4386864583 cites W4220991231 @default.
• W4386864583 cites W4280646683 @default.
• W4386864583 cites W4283704002 @default.
• W4386864583 cites W4291283682 @default.
• W4386864583 cites W4309721563 @default.
• W4386864583 cites W4322738920 @default.
• W4386864583 cites W4361282550 @default.
• W4386864583 cites W4367397086 @default.
• W4386864583 cites W78680022 @default.
• W4386864583 doi "https://doi.org/10.1093/g3journal/jkad215" @default.

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