Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386864761> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W4386864761 abstract "This systematic review and meta-analysis aimed to evaluate the performance of existing externally validated prediction models for pre-eclampsia (specifically for any- early- late-onset and preterm pre-eclampsia).A systematic search was conducted in five databases (MEDLINE, Embase, Emcare, CINAHL, and Maternity and Infant Care Database) to identify studies based on Population, Index model, Comparator, Outcome, Timing, and Setting (PICOTS) approach until May 20, 2023. We extracted data using the CHARMS checklist and appraised risk of bias using PROBAST tool. Discrimination and calibration performance were meta-analysed when appropriate.Twenty-three publications reported 52 externally validated prediction models on pre-eclampsia (twenty any-onset, seventeen early-onset, fourteen late-onset, and one preterm pre-eclampsia). No model had the same set of predictors. Fifteen, two, and three any-onset pre-eclampsia models were externally validated once, twice, and thrice, respectively, and the Fetal Medicine Foundation (FMF) preterm model was widely validated in sixteen different settings. The most common predictors were maternal characteristics (pre-pregnancy BMI, prior pre-eclampsia, family history of pre-eclampsia, chronic medical conditions, and ethnicity) and biomarkers (uterine artery pulsatility index and pregnancy-associated plasma protein-A). The model for preterm pre-eclampsia (triple test FMF) had the best performances with a pooled area under the receiver operating characteristics curve (AUROC) of 0.90 (95% prediction interval (PI) 0.76 - 0.96) and was well-calibrated. The other models generally had poor to fair discrimination performance (AUROC median 0.66, range 0.53 to 0.77) and were overfitted in calibration after external validation. Apart from the FMF model, only the two most validated models in any-onset pre-eclampsia using isolated maternal characteristics, produced reasonable pooled AUROCs of 0.71 (95% PI 0.66 - 0.76) and 0.73 (0.55 - 0.86).Existing externally validated prediction models for any-, early-, and late-onset pre-eclampsia have limited discrimination and calibration performance with inconsistent input variables. The triple test FMF model had excellent discrimination performance in predicting preterm pre-eclampsia in numerous settings, but the inclusion of specialised biomarkers may limit feasibility and implementation outside of high-resource settings. This article is protected by copyright. All rights reserved." @default.
- W4386864761 created "2023-09-20" @default.
- W4386864761 creator A5020019905 @default.
- W4386864761 creator A5022380857 @default.
- W4386864761 creator A5039259985 @default.
- W4386864761 creator A5040796127 @default.
- W4386864761 creator A5043209053 @default.
- W4386864761 creator A5044803652 @default.
- W4386864761 creator A5055880393 @default.
- W4386864761 creator A5069127234 @default.
- W4386864761 creator A5081226449 @default.
- W4386864761 creator A5082289384 @default.
- W4386864761 date "2023-09-19" @default.
- W4386864761 modified "2023-09-27" @default.
- W4386864761 title "Externally validated prediction models for pre‐eclampsia: systematic review and meta‐analysis" @default.
- W4386864761 doi "https://doi.org/10.1002/uog.27490" @default.
- W4386864761 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37724649" @default.
- W4386864761 hasPublicationYear "2023" @default.
- W4386864761 type Work @default.
- W4386864761 citedByCount "0" @default.
- W4386864761 crossrefType "journal-article" @default.
- W4386864761 hasAuthorship W4386864761A5020019905 @default.
- W4386864761 hasAuthorship W4386864761A5022380857 @default.
- W4386864761 hasAuthorship W4386864761A5039259985 @default.
- W4386864761 hasAuthorship W4386864761A5040796127 @default.
- W4386864761 hasAuthorship W4386864761A5043209053 @default.
- W4386864761 hasAuthorship W4386864761A5044803652 @default.
- W4386864761 hasAuthorship W4386864761A5055880393 @default.
- W4386864761 hasAuthorship W4386864761A5069127234 @default.
- W4386864761 hasAuthorship W4386864761A5081226449 @default.
- W4386864761 hasAuthorship W4386864761A5082289384 @default.
- W4386864761 hasConcept C118552586 @default.
- W4386864761 hasConcept C126322002 @default.
- W4386864761 hasConcept C131872663 @default.
- W4386864761 hasConcept C15744967 @default.
- W4386864761 hasConcept C17744445 @default.
- W4386864761 hasConcept C180747234 @default.
- W4386864761 hasConcept C199539241 @default.
- W4386864761 hasConcept C27415008 @default.
- W4386864761 hasConcept C2779234561 @default.
- W4386864761 hasConcept C2779356329 @default.
- W4386864761 hasConcept C2779473830 @default.
- W4386864761 hasConcept C2781145037 @default.
- W4386864761 hasConcept C2781276381 @default.
- W4386864761 hasConcept C2908647359 @default.
- W4386864761 hasConcept C44249647 @default.
- W4386864761 hasConcept C54355233 @default.
- W4386864761 hasConcept C58471807 @default.
- W4386864761 hasConcept C71924100 @default.
- W4386864761 hasConcept C86803240 @default.
- W4386864761 hasConcept C95190672 @default.
- W4386864761 hasConcept C99454951 @default.
- W4386864761 hasConceptScore W4386864761C118552586 @default.
- W4386864761 hasConceptScore W4386864761C126322002 @default.
- W4386864761 hasConceptScore W4386864761C131872663 @default.
- W4386864761 hasConceptScore W4386864761C15744967 @default.
- W4386864761 hasConceptScore W4386864761C17744445 @default.
- W4386864761 hasConceptScore W4386864761C180747234 @default.
- W4386864761 hasConceptScore W4386864761C199539241 @default.
- W4386864761 hasConceptScore W4386864761C27415008 @default.
- W4386864761 hasConceptScore W4386864761C2779234561 @default.
- W4386864761 hasConceptScore W4386864761C2779356329 @default.
- W4386864761 hasConceptScore W4386864761C2779473830 @default.
- W4386864761 hasConceptScore W4386864761C2781145037 @default.
- W4386864761 hasConceptScore W4386864761C2781276381 @default.
- W4386864761 hasConceptScore W4386864761C2908647359 @default.
- W4386864761 hasConceptScore W4386864761C44249647 @default.
- W4386864761 hasConceptScore W4386864761C54355233 @default.
- W4386864761 hasConceptScore W4386864761C58471807 @default.
- W4386864761 hasConceptScore W4386864761C71924100 @default.
- W4386864761 hasConceptScore W4386864761C86803240 @default.
- W4386864761 hasConceptScore W4386864761C95190672 @default.
- W4386864761 hasConceptScore W4386864761C99454951 @default.
- W4386864761 hasLocation W43868647611 @default.
- W4386864761 hasLocation W43868647612 @default.
- W4386864761 hasOpenAccess W4386864761 @default.
- W4386864761 hasPrimaryLocation W43868647611 @default.
- W4386864761 hasRelatedWork W1605509685 @default.
- W4386864761 hasRelatedWork W1993079004 @default.
- W4386864761 hasRelatedWork W2001631557 @default.
- W4386864761 hasRelatedWork W2043432888 @default.
- W4386864761 hasRelatedWork W2508083898 @default.
- W4386864761 hasRelatedWork W2611007169 @default.
- W4386864761 hasRelatedWork W2983236929 @default.
- W4386864761 hasRelatedWork W3206437985 @default.
- W4386864761 hasRelatedWork W4226339494 @default.
- W4386864761 hasRelatedWork W3126899862 @default.
- W4386864761 isParatext "false" @default.
- W4386864761 isRetracted "false" @default.
- W4386864761 workType "article" @default.