FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386865552> ?p ?o ?g. }

• W4386865552 abstract "The objective of this study was to evaluate the clinical efficacy of early and delayed renal replacement therapy (RRT) in patients with sepsis-associated acute kidney injury (AKI).We searched three databases (PubMed, Web of Science, and Cochrane) for randomised controlled trials and cohort studies published up to March 28, 2022, and manually searched for relevant references. We included data from adults older than 18 years of age with sepsis-associated AKI. The Newcastle-Ottawa Scale and the Cochrane Risk of Bias tool were used for quality assessment. The primary outcome was 28-day mortality. Relative risk (RR), mean difference (MD), and 95% confidence interval (CI) were used for meta-analysis.There were a total of 3648 patients from four randomised controlled trials and eight cohort studies. The pooled results indicated that compared to delayed RRT, early RRT had a lower 28-day mortality (RR: 0.72; 95% CI: 0.59-0.88; P = 0.001; I2 = 76%), and this result was robust according to sensitivity analysis, and no significant difference in 90-day mortality (RR: 0.80; 95% CI: 0.64-1.00; P = 0.05; I2 = 82%),180-day mortality (RR: 1.07; 95% CI: 0.93-1.23; P = 0.36; I2 = 0%), length of intensive care unit stay (MD - 0.94; 95% CI -2.43-0.55; P = 0.22; I2 = 0%), length of hospital stay (MD - 1.02; 95% CI -4.21-2.17; P = 0.53; I2 = 0%), and RRT dependence was found among survivors at 28 days (RR: 1.21; 95% CI: 0.73-2.00; P = 0.47; I2 = 0%). Subgroup analysis of 28-day mortality showed that patients with sepsis-associated AKI who received early RRT at Kidney Disease: Improving Global Outcomes stage 2 or Sequential Organ Failure Assessment score ≤12 had a better chance of survival.Early RRT may be beneficial to the 28-day short-term survival rate of patients with sepsis-associated AKI in Kidney Disease: Improving Global Outcomes stage 2 and having Sequential Organ Failure Assessment score less than or equal to 12 but has no significant effect on long-term survival, length of intensive care unit stay, the total length of hospital stay, and 28-day RRT dependence of survivors. These results still need to be confirmed by more large-scale randomised controlled studies." @default.
• W4386865552 created "2023-09-20" @default.
• W4386865552 creator A5031500020 @default.
• W4386865552 creator A5061188546 @default.
• W4386865552 creator A5079643976 @default.
• W4386865552 creator A5085829195 @default.
• W4386865552 date "2023-09-01" @default.
• W4386865552 modified "2023-09-28" @default.
• W4386865552 title "Timing of renal replacement therapy in patients with sepsis-associated acute kidney injury: A systematic review and meta-analysis" @default.
• W4386865552 cites W1893908667 @default.
• W4386865552 cites W1998845280 @default.
• W4386865552 cites W2018351895 @default.
• W4386865552 cites W2019442978 @default.
• W4386865552 cites W2044664374 @default.
• W4386865552 cites W2063317977 @default.
• W4386865552 cites W2098923148 @default.
• W4386865552 cites W2101082552 @default.
• W4386865552 cites W2104487058 @default.
• W4386865552 cites W2106983032 @default.
• W4386865552 cites W2110075486 @default.
• W4386865552 cites W2116475791 @default.
• W4386865552 cites W2120754974 @default.
• W4386865552 cites W2141559993 @default.
• W4386865552 cites W2142349448 @default.
• W4386865552 cites W2149687213 @default.
• W4386865552 cites W2157823046 @default.
• W4386865552 cites W2280404143 @default.
• W4386865552 cites W2345809966 @default.
• W4386865552 cites W2380810418 @default.
• W4386865552 cites W2395969030 @default.
• W4386865552 cites W2563677781 @default.
• W4386865552 cites W2599350803 @default.
• W4386865552 cites W2604405221 @default.
• W4386865552 cites W2724317418 @default.
• W4386865552 cites W2784573678 @default.
• W4386865552 cites W2896124705 @default.
• W4386865552 cites W2950811882 @default.
• W4386865552 cites W2969763838 @default.
• W4386865552 cites W2995150248 @default.
• W4386865552 cites W3020371609 @default.
• W4386865552 cites W3042687084 @default.
• W4386865552 cites W3118871979 @default.
• W4386865552 cites W3123893780 @default.
• W4386865552 cites W3173952737 @default.
• W4386865552 doi "https://doi.org/10.1016/j.aucc.2023.06.011" @default.
• W4386865552 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37734999" @default.
• W4386865552 hasPublicationYear "2023" @default.
• W4386865552 type Work @default.
• W4386865552 citedByCount "0" @default.
• W4386865552 crossrefType "journal-article" @default.
• W4386865552 hasAuthorship W4386865552A5031500020 @default.
• W4386865552 hasAuthorship W4386865552A5061188546 @default.
• W4386865552 hasAuthorship W4386865552A5079643976 @default.
• W4386865552 hasAuthorship W4386865552A5085829195 @default.
• W4386865552 hasConcept C126322002 @default.
• W4386865552 hasConcept C168563851 @default.
• W4386865552 hasConcept C201903717 @default.
• W4386865552 hasConcept C2776376669 @default.
• W4386865552 hasConcept C2778384902 @default.
• W4386865552 hasConcept C2779541074 @default.
• W4386865552 hasConcept C2780472472 @default.
• W4386865552 hasConcept C44249647 @default.
• W4386865552 hasConcept C71924100 @default.
• W4386865552 hasConcept C72563966 @default.
• W4386865552 hasConcept C82789193 @default.
• W4386865552 hasConcept C95190672 @default.
• W4386865552 hasConceptScore W4386865552C126322002 @default.
• W4386865552 hasConceptScore W4386865552C168563851 @default.
• W4386865552 hasConceptScore W4386865552C201903717 @default.
• W4386865552 hasConceptScore W4386865552C2776376669 @default.
• W4386865552 hasConceptScore W4386865552C2778384902 @default.
• W4386865552 hasConceptScore W4386865552C2779541074 @default.
• W4386865552 hasConceptScore W4386865552C2780472472 @default.
• W4386865552 hasConceptScore W4386865552C44249647 @default.
• W4386865552 hasConceptScore W4386865552C71924100 @default.
• W4386865552 hasConceptScore W4386865552C72563966 @default.
• W4386865552 hasConceptScore W4386865552C82789193 @default.
• W4386865552 hasConceptScore W4386865552C95190672 @default.
• W4386865552 hasLocation W43868655521 @default.
• W4386865552 hasLocation W43868655522 @default.
• W4386865552 hasOpenAccess W4386865552 @default.
• W4386865552 hasPrimaryLocation W43868655521 @default.
• W4386865552 hasRelatedWork W135164154 @default.
• W4386865552 hasRelatedWork W2171938400 @default.
• W4386865552 hasRelatedWork W2598584487 @default.
• W4386865552 hasRelatedWork W2617679349 @default.
• W4386865552 hasRelatedWork W2889237166 @default.
• W4386865552 hasRelatedWork W3007491672 @default.
• W4386865552 hasRelatedWork W3029764792 @default.
• W4386865552 hasRelatedWork W3194567935 @default.
• W4386865552 hasRelatedWork W4316040074 @default.
• W4386865552 hasRelatedWork W4382789480 @default.
• W4386865552 isParatext "false" @default.
• W4386865552 isRetracted "false" @default.
• W4386865552 workType "article" @default.