Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386893209> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W4386893209 endingPage "142" @default.
- W4386893209 startingPage "136" @default.
- W4386893209 abstract "Granuloma annulare (GA) is a chronic inflammatory necrobiotic granulomatous skin disease, which is based on a delayed hypersensitivity reaction caused by the production of interferon- (IFN-) by tissue macrophages and th1-limocytes, tumor necrosis factor- (TNF-) and matrix metalloproteinases (MMP), which leads to the degradation of connective tissue.
 The most frequent form of GA if localized which is characterized clinically by grouped papules and plaques of red or pink color on the extremities. although disseminated variants of disease occur in 15% of all cases of ag. in contrast to the practically asymptomatic course of the localized form, typical signs of disseminated form are intensive sense of itching, the presence of at least ten foci of skin lesions, recurrent and resistance to treatment course.
 A 53-year-old female patient with a long-term recurrent course of annular granuloma after a weak clinical response to therapy with pentoxifilin, methotrexate and azathioprine turned to the dermatology department of the university hospital. In light of the lack of satisfactory treatment options anti-cytokine therapy with adalimumab was recommended at a daily dosage of 80 mg, once a week, for 2 weeks, then 1 time every two weeks for 1.5 months. Already on the 5th day after receiving the first injection, the patient reported that the feeling of itching disappeared. By the end of the second week of the induction phase of biotherapy, it became obvious that new rashes did not appear, and the old elements of the skin rash had significantly flattened, turned pale and decreased in volume. After the second week of consolidated therapy, the dermatologist confirmed the convalescence." @default.
- W4386893209 created "2023-09-21" @default.
- W4386893209 creator A5021680113 @default.
- W4386893209 creator A5023143821 @default.
- W4386893209 creator A5032744806 @default.
- W4386893209 creator A5044362467 @default.
- W4386893209 creator A5068999553 @default.
- W4386893209 creator A5086740721 @default.
- W4386893209 creator A5089141528 @default.
- W4386893209 date "2023-10-16" @default.
- W4386893209 modified "2023-10-18" @default.
- W4386893209 title "Successful treatment of disseminated granuloma annulare with adalimumab: a case report." @default.
- W4386893209 cites W1965049677 @default.
- W4386893209 cites W2020979111 @default.
- W4386893209 cites W2591897885 @default.
- W4386893209 cites W2613601657 @default.
- W4386893209 cites W2772252307 @default.
- W4386893209 cites W2908997823 @default.
- W4386893209 cites W2959031686 @default.
- W4386893209 cites W2970649313 @default.
- W4386893209 cites W3042771802 @default.
- W4386893209 cites W3044373291 @default.
- W4386893209 cites W3196345437 @default.
- W4386893209 doi "https://doi.org/10.25208/vdv1368" @default.
- W4386893209 hasPublicationYear "2023" @default.
- W4386893209 type Work @default.
- W4386893209 citedByCount "0" @default.
- W4386893209 crossrefType "journal-article" @default.
- W4386893209 hasAuthorship W4386893209A5021680113 @default.
- W4386893209 hasAuthorship W4386893209A5023143821 @default.
- W4386893209 hasAuthorship W4386893209A5032744806 @default.
- W4386893209 hasAuthorship W4386893209A5044362467 @default.
- W4386893209 hasAuthorship W4386893209A5068999553 @default.
- W4386893209 hasAuthorship W4386893209A5086740721 @default.
- W4386893209 hasAuthorship W4386893209A5089141528 @default.
- W4386893209 hasBestOaLocation W43868932091 @default.
- W4386893209 hasConcept C141071460 @default.
- W4386893209 hasConcept C142724271 @default.
- W4386893209 hasConcept C16005928 @default.
- W4386893209 hasConcept C2777910003 @default.
- W4386893209 hasConcept C2778570526 @default.
- W4386893209 hasConcept C2779134260 @default.
- W4386893209 hasConcept C2779470898 @default.
- W4386893209 hasConcept C2779923671 @default.
- W4386893209 hasConcept C2780132546 @default.
- W4386893209 hasConcept C2780140890 @default.
- W4386893209 hasConcept C71924100 @default.
- W4386893209 hasConceptScore W4386893209C141071460 @default.
- W4386893209 hasConceptScore W4386893209C142724271 @default.
- W4386893209 hasConceptScore W4386893209C16005928 @default.
- W4386893209 hasConceptScore W4386893209C2777910003 @default.
- W4386893209 hasConceptScore W4386893209C2778570526 @default.
- W4386893209 hasConceptScore W4386893209C2779134260 @default.
- W4386893209 hasConceptScore W4386893209C2779470898 @default.
- W4386893209 hasConceptScore W4386893209C2779923671 @default.
- W4386893209 hasConceptScore W4386893209C2780132546 @default.
- W4386893209 hasConceptScore W4386893209C2780140890 @default.
- W4386893209 hasConceptScore W4386893209C71924100 @default.
- W4386893209 hasIssue "4" @default.
- W4386893209 hasLocation W43868932091 @default.
- W4386893209 hasOpenAccess W4386893209 @default.
- W4386893209 hasPrimaryLocation W43868932091 @default.
- W4386893209 hasRelatedWork W2002219705 @default.
- W4386893209 hasRelatedWork W2013489845 @default.
- W4386893209 hasRelatedWork W2027209100 @default.
- W4386893209 hasRelatedWork W2056963163 @default.
- W4386893209 hasRelatedWork W2316822442 @default.
- W4386893209 hasRelatedWork W2563362192 @default.
- W4386893209 hasRelatedWork W2901883939 @default.
- W4386893209 hasRelatedWork W3097370318 @default.
- W4386893209 hasRelatedWork W4241503027 @default.
- W4386893209 hasRelatedWork W4318183227 @default.
- W4386893209 hasVolume "99" @default.
- W4386893209 isParatext "false" @default.
- W4386893209 isRetracted "false" @default.
- W4386893209 workType "article" @default.