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- W4386934033 endingPage "2581" @default.
- W4386934033 startingPage "2581" @default.
- W4386934033 abstract "Osteoporosis is a common skeletal disorder which can severely limit one's ability to complete daily tasks due to the increased risk of bone fractures, reducing quality of life. Spinal cord injury (SCI) can also result in osteoporosis and sarcopenia. Most individuals experience sarcopenia and osteoporosis due to advancing age; however, individuals with SCI experience more rapid and debilitating levels of muscle and bone loss due to neurogenic factors, musculoskeletal disuse, and cellular/molecular events. Thus, preserving and maintaining bone mass after SCI is crucial to decreasing the risk of fragility and fracture in vulnerable SCI populations. Recent studies have provided an improved understanding of the pathophysiology and risk factors related to musculoskeletal loss after SCI. Pharmacological and non-pharmacological therapies have also provided for the reduction in or elimination of neurogenic bone loss after SCI. This review article will discuss the pathophysiology and risk factors of muscle and bone loss after SCI, including the mechanisms that may lead to muscle and bone loss after SCI. This review will also focus on current and future pharmacological and non-pharmacological therapies for reducing or eliminating neurogenic bone loss following SCI." @default.
- W4386934033 created "2023-09-22" @default.
- W4386934033 creator A5018309282 @default.
- W4386934033 creator A5065760036 @default.
- W4386934033 creator A5080187908 @default.
- W4386934033 creator A5088053417 @default.
- W4386934033 date "2023-09-20" @default.
- W4386934033 modified "2023-10-17" @default.
- W4386934033 title "Rehabilitation: Neurogenic Bone Loss after Spinal Cord Injury" @default.
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