Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386945139> ?p ?o ?g. }
- W4386945139 abstract "Shenlingbaizhu granule, a Traditional Chinese Medicine prescription comprising Renshen, Gancao, and Shanyao, is widely consumed in China nowadays.The study tries to propose pharmacopoeia quality markers (Q-markers) to prevent counterfeiting involving Renshen, Gancao, and Shanyao.A novel strategy, that is, library-based ultra-high-performance liquid chromatography-quadrupole-orbitrap mass spectrometry, was used to analyse the lyophilised aqueous powder of Shenlingbaizhu granule. Subsequently, quantum chemistry calculation and UV-vis spectra scanning were also performed through theoretical or experimental approaches.Thirty-two isomers have been strictly distinguished, especially positional isomeric isochlorogenic acid B versus isochlorogenic acid C, positional isomeric schaftoside versus isoschaftoside, positional isomeric ginsenoside Rg2 versus 20S-ginsenoside Rg3, and stereoisomeric 20S-ginsenoside Rg3 versus 20R-ginsenoside Rg3. Seventeen compounds were unexpectedly observed, particularly scoparone and pectolinarigenin, while a total of 76 bioactive compounds have been putatively identified in the study. The quantum chemistry calculation and UV-vis spectra scanning results revealed that glycyrrhizic acid, ginsenoside Re, ginsenoside Rb1, and diosgenin displayed different dipole moment values and maximum absorption wavelengths from each other.The study recommends glycyrrhizic acid, ginsenoside Re, ginsenoside Rb1, and diosgenin as four anti-counterfeiting Q-markers for the pharmacopoeia. The anti-counterfeiting Q-markers can be detected using conventional HPLC. The observation of 17 unexpected compounds updates our knowledge regarding the bioactives of Shenlingbaizhu granule." @default.
- W4386945139 created "2023-09-23" @default.
- W4386945139 creator A5036867860 @default.
- W4386945139 creator A5043054254 @default.
- W4386945139 creator A5045950755 @default.
- W4386945139 creator A5054410132 @default.
- W4386945139 creator A5056648062 @default.
- W4386945139 creator A5069658558 @default.
- W4386945139 creator A5077378089 @default.
- W4386945139 date "2023-09-21" @default.
- W4386945139 modified "2023-10-07" @default.
- W4386945139 title "Proposing anti‐counterfeiting pharmacopoeia quality markers for <i>Shenlingbaizhu</i> granule based on UHPLC‐Q‐orbitrap‐MS identification" @default.
- W4386945139 cites W1976481305 @default.
- W4386945139 cites W1987723637 @default.
- W4386945139 cites W2054960475 @default.
- W4386945139 cites W2068380311 @default.
- W4386945139 cites W2091439890 @default.
- W4386945139 cites W2117802918 @default.
- W4386945139 cites W2132525235 @default.
- W4386945139 cites W2151247210 @default.
- W4386945139 cites W2408650941 @default.
- W4386945139 cites W2598815405 @default.
- W4386945139 cites W2727362802 @default.
- W4386945139 cites W2750026604 @default.
- W4386945139 cites W2788239757 @default.
- W4386945139 cites W2789377711 @default.
- W4386945139 cites W2808954143 @default.
- W4386945139 cites W2895206589 @default.
- W4386945139 cites W2897913093 @default.
- W4386945139 cites W2899512527 @default.
- W4386945139 cites W2915711045 @default.
- W4386945139 cites W2953784146 @default.
- W4386945139 cites W2979795026 @default.
- W4386945139 cites W3030469974 @default.
- W4386945139 cites W3129177446 @default.
- W4386945139 cites W3156463639 @default.
- W4386945139 cites W3163086556 @default.
- W4386945139 cites W3176839748 @default.
- W4386945139 cites W3184601619 @default.
- W4386945139 cites W3186902551 @default.
- W4386945139 cites W4200236759 @default.
- W4386945139 cites W4210327535 @default.
- W4386945139 cites W4220657227 @default.
- W4386945139 cites W4220801253 @default.
- W4386945139 cites W4281778286 @default.
- W4386945139 cites W4282921443 @default.
- W4386945139 cites W4285744845 @default.
- W4386945139 cites W4294719198 @default.
- W4386945139 cites W4307942978 @default.
- W4386945139 cites W4309613359 @default.
- W4386945139 cites W4311834223 @default.
- W4386945139 cites W4312127912 @default.
- W4386945139 cites W4319160737 @default.
- W4386945139 cites W4381736639 @default.
- W4386945139 doi "https://doi.org/10.1002/pca.3284" @default.
- W4386945139 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37735858" @default.
- W4386945139 hasPublicationYear "2023" @default.
- W4386945139 type Work @default.
- W4386945139 citedByCount "0" @default.
- W4386945139 crossrefType "journal-article" @default.
- W4386945139 hasAuthorship W4386945139A5036867860 @default.
- W4386945139 hasAuthorship W4386945139A5043054254 @default.
- W4386945139 hasAuthorship W4386945139A5045950755 @default.
- W4386945139 hasAuthorship W4386945139A5054410132 @default.
- W4386945139 hasAuthorship W4386945139A5056648062 @default.
- W4386945139 hasAuthorship W4386945139A5069658558 @default.
- W4386945139 hasAuthorship W4386945139A5077378089 @default.
- W4386945139 hasConcept C114793014 @default.
- W4386945139 hasConcept C121332964 @default.
- W4386945139 hasConcept C127313418 @default.
- W4386945139 hasConcept C142724271 @default.
- W4386945139 hasConcept C162356407 @default.
- W4386945139 hasConcept C179998833 @default.
- W4386945139 hasConcept C185592680 @default.
- W4386945139 hasConcept C204787440 @default.
- W4386945139 hasConcept C2776539398 @default.
- W4386945139 hasConcept C2779232237 @default.
- W4386945139 hasConcept C2780841973 @default.
- W4386945139 hasConcept C43617362 @default.
- W4386945139 hasConcept C49760210 @default.
- W4386945139 hasConcept C71240020 @default.
- W4386945139 hasConcept C71924100 @default.
- W4386945139 hasConcept C74650414 @default.
- W4386945139 hasConcept C88463166 @default.
- W4386945139 hasConceptScore W4386945139C114793014 @default.
- W4386945139 hasConceptScore W4386945139C121332964 @default.
- W4386945139 hasConceptScore W4386945139C127313418 @default.
- W4386945139 hasConceptScore W4386945139C142724271 @default.
- W4386945139 hasConceptScore W4386945139C162356407 @default.
- W4386945139 hasConceptScore W4386945139C179998833 @default.
- W4386945139 hasConceptScore W4386945139C185592680 @default.
- W4386945139 hasConceptScore W4386945139C204787440 @default.
- W4386945139 hasConceptScore W4386945139C2776539398 @default.
- W4386945139 hasConceptScore W4386945139C2779232237 @default.
- W4386945139 hasConceptScore W4386945139C2780841973 @default.
- W4386945139 hasConceptScore W4386945139C43617362 @default.
- W4386945139 hasConceptScore W4386945139C49760210 @default.
- W4386945139 hasConceptScore W4386945139C71240020 @default.
- W4386945139 hasConceptScore W4386945139C71924100 @default.
- W4386945139 hasConceptScore W4386945139C74650414 @default.